Recent strategies and advances in the fabrication of nano lipid carriers and their application towards brain targeting
In last two decades, the lipid nanocarriers have been extensively investigated for their drug
targeting efficiency towards the critical areas of the human body like CNS, cardiac region …
targeting efficiency towards the critical areas of the human body like CNS, cardiac region …
Increased mortality in schizophrenia due to cardiovascular disease–a non-systematic review of epidemiology, possible causes, and interventions
PA Ringen, JA Engh, AB Birkenaes, I Dieset… - Frontiers in …, 2014 - frontiersin.org
Background: Schizophrenia is among the major causes of disability worldwide and the
mortality from cardiovascular disease (CVD) is significantly elevated. There is a growing …
mortality from cardiovascular disease (CVD) is significantly elevated. There is a growing …
Antipsychotic drugs: from receptor-binding profiles to metabolic side effects
Background: Antipsychotic-induced metabolic side effects are major concerns in
psychopharmacology and clinical psychiatry. Their pathogenetic mechanisms are still not …
psychopharmacology and clinical psychiatry. Their pathogenetic mechanisms are still not …
The current status of the ketogenic diet in psychiatry
ECS Bostock, KC Kirkby, BVM Taylor - Frontiers in psychiatry, 2017 - frontiersin.org
Background The ketogenic diet (KD) has been used in treatment-resistant epilepsy since the
1920s. It has been researched in a variety of neurological conditions in both animal models …
1920s. It has been researched in a variety of neurological conditions in both animal models …
Characterizing the shared genetic underpinnings of schizophrenia and cardiovascular disease risk factors
L Rødevand, Z Rahman, GFL Hindley… - American Journal of …, 2023 - Am Psychiatric Assoc
Objective: Schizophrenia is associated with increased risk of cardiovascular disease (CVD),
although there is variation in risk among individuals. There are indications of shared genetic …
although there is variation in risk among individuals. There are indications of shared genetic …
Targeted placental deletion of OGT recapitulates the prenatal stress phenotype including hypothalamic mitochondrial dysfunction
CL Howerton, TL Bale - Proceedings of the National …, 2014 - National Acad Sciences
Maternal stress is a key risk factor in neurodevelopmental disorders, which often have a sex
bias in severity and prevalence. We previously identified O-GlcNAc transferase (OGT) as a …
bias in severity and prevalence. We previously identified O-GlcNAc transferase (OGT) as a …
Omics-based biomarkers: application of metabolomics in neuropsychiatric disorders
S Sethi, E Brietzke - International Journal of …, 2016 - academic.oup.com
One of the major concerns of modern society is to identify putative biomarkers that serve as
a valuable early diagnostic tool to identify a subset of patients with increased risk to develop …
a valuable early diagnostic tool to identify a subset of patients with increased risk to develop …
[PDF][PDF] and type 2 diabetes mellitus
V Mamakou, A Thanopoulou… - ΕΛΛΗΝΙΚΗ …, 2018 - psychiatriki-journal.gr
Schizophrenia is associated with increased risk for type 2 diabetes mellitus, resulting in
elevated cardiovascular risk and limited life expectancy, translated into a weighted average …
elevated cardiovascular risk and limited life expectancy, translated into a weighted average …
Role of immunological factors in the pathophysiology and diagnosis of bipolar disorder: comparison with schizophrenia
AC Altamura, M Buoli, S Pozzoli - Psychiatry and clinical …, 2014 - Wiley Online Library
Several lines of evidence point to the key role of neurobiological mechanisms and shared
genetic background in schizophrenia and bipolar disorder. For both disorders …
genetic background in schizophrenia and bipolar disorder. For both disorders …
Crosstalk between schizophrenia and metabolic syndrome: The role of oxytocinergic dysfunction
KK Goh, CYA Chen, TH Wu, CH Chen… - International journal of …, 2022 - mdpi.com
The high prevalence of metabolic syndrome in persons with schizophrenia has spurred
investigational efforts to study the mechanism beneath its pathophysiology. Early psychosis …
investigational efforts to study the mechanism beneath its pathophysiology. Early psychosis …