Alzheimer's disease (AD) is a progressive neurodegenerative disorder that is characterized
by cognitive decline and the presence of two core pathologies, amyloid β plaques and …

Microglia are brain resident macrophages originated from primitive progenitor cells in the
yolk sac. Microglia can be activated within hours and recruited to the lesion site …

The emerging roles of microglia are currently being investigated in the healthy and diseased
brain with a growing interest in their diverse functions. In recent years, it has been …

Glia of the central nervous system (CNS) help to maintain homeostasis in the brain and
support efficient neuronal function. Microglia are innate immune cells of the brain that …

MicroRNAs (miRNAs) are short, non-coding RNAs that post-transcriptionally repress
translation or induce mRNA degradation of target transcripts through sequence-specific …

Microglia are highly active and vigilant housekeepers of the central nervous system that
function to promote neuronal growth and activity. With advanced age, however …

MicroRNAs (miRNAs) are small, abundant RNA molecules that constitute part of the cell's
non-coding RNA “dark matter.” In recent years, the discovery of miRNAs has revolutionised …

Age related macular degeneration (AMD) is a complex multifactorial disease caused by the
interplay of age and genetic and environmental risk factors. A common feature observed in …

The human genome encodes a vast repertoire of protein non-coding RNAs (ncRNA), some
specific to the brain. MicroRNAs, which interfere with the translation of target mRNAs, are of …

Immunosenescence, describing alterations, including decline of immune responses with
age, is comprised of inappropriate elevations, decreases, and dysregulated immune …