The human body is full of an extensive number of commensal microbes, consisting of
bacteria, viruses, and fungi, collectively termed the human microbiome. The initial …

The Janus kinase/signal transducer and activator of transcription (JAK/STAT) signaling
pathway was discovered more than a quarter-century ago. As a fulcrum of many vital cellular …

Parkinson's Disease (PD) is the second most common neurodegenerative disorder seen,
especially in the elderly. Tremor, shaking, movement problems, and difficulty with balance …

Multiple lines of evidence indicate that immune system dysfunction has a role in Parkinson
disease (PD); this evidence includes clinical and genetic associations between autoimmune …

ABSTRACT A healthy balanced diet is crucial in protecting the immune system against
infections and diseases. Poor diets, such as the Western diet, contribute to the development …

Background Previous studies have reported that gut microbiota, permeability, short-chain
fatty acids (SCFAs), and inflammation are altered in Parkinson's disease (PD), but how these …

Gut dysbiosis, a primary factor behind various gastrointestinal disorders may also augment
lipopolysaccharides, pro-inflammatory cytokines, T helper cells and monocytes causing …

In order to better understand the pathogenesis of Parkinson's Disease (PD) it is important to
consider possible contributory factors inherent to the aging process, as age-related changes …

The immune system is vital for safeguarding the human body against infections and
inflammatory diseases. The role of diet and meal patterns in modulating immune function is …

Parkinson's disease (PD) is associated with increased iron levels in the substantia nigra
(SNc). This study evaluated whether the iron chelator, deferiprone, is well tolerated, able to …