Background A notable reduction of the pneumococcal disease burden among adults was
observed after the introduction of a 7-valent pneumococcal conjugate vaccine (PCV7) in …

Seven-valent pneumococcal conjugate vaccine (PCV7) introduction and routine pediatric
use has substantially reduced the burden of Streptococcus pneumoniae disease worldwide …

Streptococcus pneumoniae (pneumococcus) frequently colonizes the human nasopharynx
and is an important cause of pneumonia, meningitis, sinusitis, and otitis media. The outer …

Background Streptococcus pneumoniae is a bacterial pathogen that colonizes the human
nasopharynx. Colonization is frequently reported to be high in young children. In this study …

ABSTRACT In Madrid, Spain, the 13-valent pneumococcal conjugate vaccine (PCV13)
replaced PCV7 in the pediatric universal vaccination calendar in June 2010. A prospective …

Nanotechnology and protein engineering helped revolutionize the invention and upgrading
of immunization carriers, as well as medicine packaging and delivery systems. Viruses have …

Alternatives to the well-established capsular polysaccharide-based vaccines against
Streptococcus pneumoniae that circumvent limitations arising from limited serotype …

Streptococcus pneumoniae is a leading cause of bacterial pneumonia, sepsis and
meningitis. Surface accessible proteins of S. pneumoniae are being explored for the …

It is important to monitor β-lactam antimicrobial nonsusceptibility trends for Streptococcus
pneumoniae to inform empirical treatment guidelines. In this study, we describe penicillin …

Introduction: The introduction of pneumococcal conjugate vaccines (PCVs) in the routine
immunization program has resulted in a significant decline in invasive pneumococcal …