Abstract Background Galectins are β-Galactose binding lectins expressed in numerous cells
and play multiple roles in various physiological and cellular functions. However, few …

Most vertebrates are infected with one or more herpesviruses and remain so for the rest of
their lives. The relationship of immunocompetent healthy host with herpesviruses may …

The β-galactoside-binding protein galectin-9 is critical in regulating the immune response,
but the mechanism by which it functions remains unclear. We have demonstrated that …

Tim-3 is highly expressed on a subset of T cells during T cell exhaustion in settings of
chronic viral infection and tumors. Using lymphocytic choriomeningitis virus (LCMV) Clone …

TIM-3 functions to enforce CD8+ T cell exhaustion, a dysfunctional state associated with the
tolerization of tumor microenvironment. Here we report apoptosis of IFN-γ competent TIM-3+ …

The galectin family consists of carbohydrate (glycan) binding proteins that are expressed by
a wide variety of cells and bind to galactose-containing glycans. Galectins can be located in …

Galectins is a family of non-classically secreted, β-galactoside-binding proteins that has
recently received considerable attention in the spatio-temporal regulation of surface 'signal …

In recent years, a critical role for β‐galactoside‐binding protein, Galectin‐9 (Gal‐9) has
emerged in infectious disease, autoimmunity, and cancer. It is a ligand for T cell …

Like other human solid tumors, nasopharyngeal carcinoma (NPC) is a tissue and a systemic
disease as much as a cell disease. Tumor cell population in NPC is highly heterogeneous …

The exact mechanisms of HSV‐1 establishment, maintenance, latency, reactivation, and
also the courses of recurrent ocular infections remain a mystery. Comprehensive …