Degradable biomedical elastomers (DBE), characterized by controlled biodegradability,
excellent biocompatibility, tailored elasticity, and favorable network design and …

Objectives The polyester/hydroxyapatite (polyester/HA) composites play an important role in
bone tissue repairing, mostly because they mimic the composition and structure of naturally …

Osteochondral injury is a common and frequent orthopedic disease that can lead to more
serious degenerative joint disease. Tissue engineering is a promising modality for …

Regenerative medicine aims to restore tissue and organ function without the use of
prosthetics and permanent implants. However, achieving this goal has been elusive, and the …

Background Osteoporosis is a chronic condition affecting patients' morbidity and mortality
and represents a big socioeconomic burden. Because stem cells can proliferate and …

Dysregulated inflammation after trauma or infection could result in the further disease and
delayed tissue reconstruction. The conventional anti-inflammatory drug treatment suffers to …

The development of biomaterials that mimicking the hydroxyapatite nanoparticles existent in
the immature bone tissue is crucial, especially to accelerate the bone remodeling and …

Recent advances in cell metabolism studies have deepened the appreciation of the role of
metabolic regulation in influencing cell behavior during differentiation, angiogenesis, and …

The burden of bone fractures demands development of effective biomaterial solutions, while
additional acute events such as noncompressible bleeding further motivate the search for …

Developing bioactive biomaterials with highly controlled functions is crucial to enhancing
their applications in regenerative medicine. Citrate-based polymers are the few bioactive …