The naked mole‐rat (Heterocephalus glaber) has fascinated zoologists for at least half a
century. It has also generated considerable biomedical interest not only because of its …

The voltage-gated sodium channel NaV1. 7 is preferentially expressed in peripheral somatic
and visceral sensory neurons, olfactory sensory neurons and sympathetic ganglion neurons …

Sensory neurons of the dorsal root ganglion (DRG) are critical for maintaining tissue
homeostasis by sensing and initiating responses to stimuli. While most preclinical studies of …

The study of diverse animal groups allows us to discern the evolution of the neurobiology of
nociception. Nociception functions as an important alarm system alerting the individual to …

The naked mole rat (Heterocephalus glaber) is a strictly subterranean, extraordinarily long-
lived eusocial mammal. Although it is the size of a mouse, its maximum lifespan exceeds 30 …

Humans detect skin temperature changes that are perceived as warm or cool. Like humans,
mice report forepaw skin warming with perceptual thresholds of less than 1° C and do not …

In order to survive, animals must avoid injury and be able to detect potentially damaging
stimuli via nociceptive mechanisms. If the injury is accompanied by a negative affective …

Chronic pain is a classic example of gene× environment interaction: inflammatory and/or
nerve injuries are known or suspected to be the etiology of most chronic pain syndromes …

Chronic pain caused by injury or disease of the nervous system (neuropathic pain) has been
linked to persistent electrical hyperactivity of the sensory neurons (nociceptors) specialized …

Antioxidants specifically addressed to mitochondria have been studied to determine if they
can decelerate senescence of organisms. For this purpose, a project has been established …