Anti-Saccharomyces cerevisiae antibodies (ASCA) are human antibodies that can be
detected using an enzyme-linked immunosorbent assay involving a mannose polymer …

Protein sulfoconjugation, or sulfation, represents a critical post-translational modification
(PTM) process that involves the attachment of sulfate groups to various positions of …

Common medications for treating inflammatory bowel disease (IBD) have limited therapeutic
efficacy and severe adverse effects. This underscores the urgent need for novel therapeutic …

Endurance athletes offer unique physiology and metabolism compared to sedentary
individuals. Athletes training at high intensities for prolonged periods are at risk for …

11 Acknowledgement: We would like to thank the Helmsley Charitable Trust for their
generous 12 support of the PROMISE consortium (PRediction and PRevention through …

Inflammatory bowel disease is associated with several genetic risk loci. Loss-of-function
mutation in the α1, 2-fucosyltransferase (fut2) gene, which alters fucosylation on the surface …

Norovirus infection can cause gastrointestinal disease in humans. Development of therapies
and vaccines against norovirus have been limited by the lack of a suitable and reliable …

Inflammatory gut disorders, including inflammatory bowel disease (IBD), can be impacted by
dietary, environmental, and genetic factors. While the incidence of IBD is increasing …

(1) Introduction: The global rise of gastrointestinal diseases, including colorectal cancer and
inflammatory bowel diseases, highlights the need to understand their causes. Diet is a …

Polycystic ovary syndrome (PCOS) is an endocrine disorder that affects fertility in women of
reproductive age, and a leading cause of anovulatory infertility. Ovarian granulosa cells are …