Recent breakthroughs in neurobiology indicate that the time is ripe to understand how
cellular-level mechanisms are related to conscious experience. Here, we highlight the …

The brain of modern humans has evolved remarkable computational abilities that enable
higher cognitive functions. These capacities are tightly linked to an increase in the size and …

The human cerebral cortex houses 1000 times more neurons than that of the cerebral cortex
of a mouse, but the possible differences in synaptic circuits between these species are still …

The active electrical properties of dendrites shape neuronal input and output and are
fundamental to brain function. However, our knowledge of active dendrites has been almost …

Dendrites have always fascinated researchers: from the artistic drawings by Ramon y Cajal
to the beautiful recordings of today, neuroscientists have been striving to unravel the …

The propagation and detection of weak signals play a vital role in the central nervous
system's information processing. In this paper, a biophysical two-compartment model is …

Synaptic transmission constitutes the primary mode of communication between neurons. It is
extensively studied in rodent but not human neocortex. We characterized synaptic …

Half a century since their discovery by Llinás and colleagues, dendritic spikes have been
observed in various neurons in different brain regions, from the neocortex and cerebellum to …

Pyramidal neurons are the most common cell type and are considered the main output
neuron in most mammalian forebrain structures. In terms of function, differences in the …

Objective. We implemented computational models of human and rat cortical neurons for
simulating the neural response to cortical stimulation with electromagnetic fields. Approach …