Oral squamous cell carcinoma (OSCC) develops on the mucosal epithelium of the oral
cavity. It accounts for approximately 90% of oral malignancies and impairs appearance …

Head and neck squamous cell carcinoma (HNSCC), an aggressive malignancy, is
characterized by high morbidity and low survival rates with limited therapeutic options …

Oral squamous cell carcinomas (OSCC) are a heterogeneous group of cancers arising from
the mucosal lining of the oral cavity. A majority of these cancers are associated with lifestyle …

Traditional therapies against cancer, chemo-and radiotherapy, have multiple limitations that
lead to treatment failure and cancer recurrence. These limitations are related to systemic …

Purpose: Vulvar cancer (VC) can be subclassified by human papillomavirus (HPV) status.
HPV-negative VCs frequently harbor TP53 mutations; however, in-depth analysis of other …

Purpose: Recently, several comprehensive genomic analyses demonstrated NOTCH1 and
NOTCH3 mutations in head and neck squamous cell carcinoma (HNSCC) in approximately …

To establish whether 4-nitroquinoline N-oxide-induced carcinogenesis mirrors the
heterogeneity of human oral squamous cell carcinoma (OSCC), we have performed …

Head and neck squamous cell carcinoma (HNSCC) defines a group of solid tumors
originating from the mucosa of the upper aerodigestive tract, pharynx, larynx, mouth, and …

Simple Summary Cancers in the head and neck region are often aggressive and poorly
respond to both irradiation or chemotherapy. Chemotherapy is currently limited by a small …

Cancer is one of the life-threatening disorders that, in spite of excellent advances in
medicine and technology, there is no effective cure for. Surgery, chemotherapy, and …