Among fungal pathogens, Cryptococcus neoformans has gained great importance among
the scientific community of several reasons. This fungus is the causative agent of …

The genus Cryptococcus contains two primary species complexes that are significant
opportunistic human fungal pathogens: C. neoformans and C. gattii. In humans …

Chaetothyriales is an ascomycetous order within Eurotiomycetes. The order is particularly
known through the black yeasts and filamentous relatives that cause opportunistic infections …

Cryptococcus neoformans causes fatal fungal meningoencephalitis. Here, we study the
roles played by fungal kinases and transcription factors (TFs) in blood-brain barrier (BBB) …

Nutrient sensing is critical for adaptation of fungi to environmental and host conditions. The
conserved cAMP/PKA signaling pathway contributes to adaptation by sensing the …

Immunocompromised individuals are at high risk of developing severe fungal infections with
high mortality rates, while fungal pathogens pose little risk to most healthy people. Poor …

There is an urgent need for new antifungal drugs to treat invasive fungal diseases.
Unfortunately, the echinocandin drugs that are fungicidal against other important fungal …

Extracellular vesicles (EVs) are membranous vesicular organelles that perform a variety of
biological functions including cell communication across different biological kingdoms. EVs …

Introduction Survival among people with HIV-associated cryptococcal meningitis (CM)
remains low, particularly among women, despite the currently optimal use of antifungal …

Cryptococcus neoformans, an opportunistic yeast pathogen, relies on a complex network of
stress response pathways that allow for proliferation in the host. In Saccharomyces …