A recurrent theme in evolutionary biology is to contrast natural selection and developmental
constraint–two forces pitted against each other as competing explanations for organismal …

An increasing number of studies demonstrate phenotypic and genetic changes in natural
populations that are subject to climate change, and there is hope that some of these …

Complex regulatory networks orchestrate most cellular processes in biological systems.
Genes in such networks are subject to expression noise, resulting in isogenic cell …

Phenotypically plastic genotypes express different phenotypes in different environments,
often in adaptive ways. The evolution of phenotypic plasticity creates developmental …

Understanding how genotypes map onto phenotypes, fitness, and eventually organisms is
arguably the next major missing piece in a fully predictive theory of evolution. We refer to this …

In this paper, we illustrate how dynamical systems theory can provide a unifying conceptual
framework for evolution of biological regulatory systems. Our argument is that the genotype …

In seasonal environments, timing of reproduction is a trait with important fitness
consequences, but we know little about the molecular mechanisms that underlie the …

Deciphering the genotype–phenotype map necessitates relating variation at the genetic
level to variation at the phenotypic level. This endeavour is inherently limited by the …

Many behaviours vary in response to the environment (biotic or abiotic) and therefore
represent an interesting form of phenotypic plasticity. Behavioural plasticity, like other plastic …

Can a history of phenotypic plasticity increase the rate of adaptation to a new environment?
Theory suggests it can be through two different mechanisms. Phenotypically plastic …