Thyroid hormone has important effects on almost every organ system and plays a crucial
role in normal growth and neurologic development. Congenital hypothyroidism affects …

Thyroid hormone has important physiologic functions in nearly every organ system. The
critical role of thyroid hormone in growth and in physical and neurologic development lends …

Untreated congenital hypothyroidism (CH) leads to intellectual disabilities. Prompt diagnosis
by newborn screening (NBS) leading to early and adequate treatment results in grossly …

Prompt identification and adequate treatment of patients with congenital hypothyroidism is
critical to optimize outcomes. New information continues to accumulate about how to …

Context The optimal levothyroxine (LT4) dose to treat congenital hypothyroidism (CH)
remains unclear, with debate over whether higher starting doses (> 10 µg/kg) are necessary …

Multiple studies have shown that in sick low birthweight infants, especially those less than
1500 g and those born before 30 weeks' gestation, there may be a delayed elevation of …

Background: Congenital hypothyroidism (CH) is the most frequent endocrine disorder during
the neonatal period, and a delay in diagnosis and treatment leads to irreversible …

Objectives We designed a multicentre open prospective randomized trial to evaluate the risk-
benefit profile of two different initial treatment schemes with levothyroxine (L-T4), 10-12.5 …

Materials and Methods This research was a cross-sectional study of 41 children with CH
who consumed LT4 for at least 3 months during March 2019-December 2019. The quality of …

Background: Congenital hypothyroidism (CH) is the most common preventable cause of
intellectual disability. The recommended starting dose of levothyroxine (LT4) is between 10 …