Global incidence and mortality of severe fungal disease
DW Denning - The Lancet Infectious Diseases, 2024 - thelancet.com
Current estimates of fungal disease incidence and mortality are imprecise. Population at risk
denominators were used to estimate annual incidence for 2019–21. Extensive literature …
denominators were used to estimate annual incidence for 2019–21. Extensive literature …
Evolution of the human pathogenic lifestyle in fungi
A Rokas - Nature Microbiology, 2022 - nature.com
Fungal pathogens cause more than a billion human infections every year, resulting in more
than 1.6 million deaths annually. Understanding the natural history and evolutionary ecology …
than 1.6 million deaths annually. Understanding the natural history and evolutionary ecology …
Nanotechnology-based ocular drug delivery systems: recent advances and future prospects
S Li, L Chen, Y Fu - Journal of Nanobiotechnology, 2023 - Springer
Ocular drug delivery has constantly challenged ophthalmologists and drug delivery
scientists due to various anatomical and physiological barriers. Static and dynamic ocular …
scientists due to various anatomical and physiological barriers. Static and dynamic ocular …
Cell wall destruction and internal cascade synergistic antifungal strategy for fungal keratitis
Y Ye, J He, H Wang, W Li, Q Wang, C Luo, X Tang… - ACS …, 2022 - ACS Publications
Fungal keratitis is one of the most common blindness-causing diseases, but clinical
antifungal treatment remains a challenge. The fungal cell wall and biofilm matrix which …
antifungal treatment remains a challenge. The fungal cell wall and biofilm matrix which …
Drug delivery to the anterior segment of the eye: A review of current and future treatment strategies
Research in the development of ophthalmic drug formulations and innovative technologies
over the past few decades has been directed at improving the penetration of medications …
over the past few decades has been directed at improving the penetration of medications …
[HTML][HTML] The global epidemiology and clinical diagnosis of Acanthamoeba keratitis
Y Zhang, X Xu, Z Wei, K Cao, Z Zhang… - Journal of Infection and …, 2023 - Elsevier
Acanthamoeba keratitis is a rare parasitic infection of the cornea that can lead to permanent
blindness if not diagnosed and treated promptly. We collected data on the incidences of …
blindness if not diagnosed and treated promptly. We collected data on the incidences of …
Visualized gallium/lyticase‐integrated antifungal strategy for fungal keratitis treatment
Fungal keratitis has been one of the common corneal infections that causes blindness, but
an effective antifungal strategy remains a challenge. The exopolysaccharides both in the …
an effective antifungal strategy remains a challenge. The exopolysaccharides both in the …
[HTML][HTML] Mycotic keratitis—a global threat from the filamentous fungi
JJ Hoffman, MJ Burton, A Leck - Journal of Fungi, 2021 - mdpi.com
Mycotic or fungal keratitis (FK) is a sight-threatening disease, caused by infection of the
cornea by filamentous fungi or yeasts. In tropical, low and middle-income countries, it …
cornea by filamentous fungi or yeasts. In tropical, low and middle-income countries, it …
A host defense peptide mimetic, brilacidin, potentiates caspofungin antifungal activity against human pathogenic fungi
TF Dos Reis, PA De Castro, RW Bastos… - Nature …, 2023 - nature.com
Fungal infections cause more than 1.5 million deaths a year. Due to emerging antifungal
drug resistance, novel strategies are urgently needed to combat life-threatening fungal …
drug resistance, novel strategies are urgently needed to combat life-threatening fungal …
PANoptosis: Mechanisms, biology, and role in disease
X Sun, Y Yang, X Meng, J Li, X Liu… - Immunological …, 2024 - Wiley Online Library
Cell death can be executed through distinct subroutines. PANoptosis is a unique
inflammatory cell death modality involving the interactions between pyroptosis, apoptosis …
inflammatory cell death modality involving the interactions between pyroptosis, apoptosis …