Anxiety disorders and GABA neurotransmission: a disturbance of modulation

P Nuss - Neuropsychiatric disease and treatment, 2015 - Taylor & Francis
Lines of evidence coming from many branches of neuroscience indicate that anxiety
disorders arise from a dysfunction in the modulation of brain circuits which regulate …

Amygdala microcircuits controlling learned fear

S Duvarci, D Pare - Neuron, 2014 - cell.com
We review recent work on the role of intrinsic amygdala networks in the regulation of
classically conditioned defensive behaviors, commonly known as conditioned fear. These …

Plastic synaptic networks of the amygdala for the acquisition, expression, and extinction of conditioned fear

HC Pape, D Pare - Physiological reviews, 2010 - journals.physiology.org
The last 10 years have witnessed a surge of interest for the mechanisms underlying the
acquisition and extinction of classically conditioned fear responses. In part, this results from …

Psychobiological mechanisms of resilience and vulnerability: implications for successful adaptation to extreme stress

DS Charney - American journal of Psychiatry, 2004 - Am Psychiatric Assoc
OBJECTIVE: Most research on the effects of severe psychological stress has focused on
stress-related psychopathology. Here, the author develops psychobiological models of …

The amygdaloid complex: anatomy and physiology

P Sah, ESL Faber… - Physiological …, 2003 - journals.physiology.org
Sah, P., ESL Faber, M. Lopez de Armentia, and J. Power. The Amygdaloid Complex:
Anatomy and Physiology. Physiol Rev 83: 803–834, 2003; 10.1152/physrev. 00002.2003 …

Neurons in medial prefrontal cortex signal memory for fear extinction

MR Milad, GJ Quirk - Nature, 2002 - nature.com
Conditioned fear responses to a tone previously paired with a shock diminish if the tone is
repeatedly presented without the shock, a process known as extinction. Since Pavlov it has …

Neural and cellular mechanisms of fear and extinction memory formation

CA Orsini, S Maren - Neuroscience & Biobehavioral Reviews, 2012 - Elsevier
Over the course of natural history, countless animal species have evolved adaptive
behavioral systems to cope with dangerous situations and promote survival. Emotional …

New vistas on amygdala networks in conditioned fear

D Paré, GJ Quirk, JE Ledoux - Journal of neurophysiology, 2004 - journals.physiology.org
It is currently believed that the acquisition of classically conditioned fear involves
potentiation of conditioned thalamic inputs in the lateral amygdala (LA). In turn, LA cells …

Psychobiological mechanisms of resilience: Relevance to prevention and treatment of stress-related psychopathology

MEM Haglund, PS Nestadt, NS Cooper… - Development and …, 2007 - cambridge.org
Resilience refers to the ability to successfully adapt to stressors, maintaining psychological
well-being in the face of adversity. Recent years have seen a great deal of research into the …

Electrical stimulation of medial prefrontal cortex reduces conditioned fear in a temporally specific manner.

MR Milad, I Vidal-Gonzalez, GJ Quirk - Behavioral neuroscience, 2004 - psycnet.apa.org
The authors recently showed that extinction of auditory fear conditioning leads to
potentiation of tone-evoked activity of neurons in the infralimbic (IL) subregion of the medial …