Flavonoids are plant pigments that are synthesised from phenylalanine, generally display
marvelous colors known from flower petals, mostly emit brilliant fluorescence when they are …

Background. Phase II biotransformation reactions (also 'conjugation reactions') generally
serve as a detoxifying step in drug metabolism. Phase II drug metabolising enzymes are …

Modern epidemiological and interventional studies have demonstrated that various
bioactivities including antioxidant, antiproliferative, immune-regulatory, hormonal-regulation …

Flavan-3-ols, occurring in monomeric, as well as in oligomeric and polymeric forms (also
known as condensed tannins or proanthocyanidins), are among the most abundant and …

The bioactivities, dietary sources, bioavailability, metabolism, and epidemiology of 3
flavonoids, quercetin, hesperetin, and naringenin, are reviewed. The use of their plasma …

Glucuronidation is a listed clearance mechanism for 1 in 10 of the top 200 prescribed drugs.
The objective of this article is to encourage those studying ligand interactions with UDP …

UDP-glucuronosyltransferase (UGT) enzymes catalyze the conjugation of various
endogenous substances (eg, bilirubin) and exogenous compounds (eg, drugs). The human …

Aspirin and other non-steroidal anti-inflammatory drugs (NSAIDs) show indisputable
promise as chemopreventive agents. Possible targets include cancers of the colon, stomach …

UDP-glucuronosyltransferase (UGT) and esterases are recognized as the most important
non-P450 enzymes because of their high contribution to drug metabolism. UGTs catalyze …

Glucuronidation represents a major pathway which enhances the elimination of many
lipophilic xenobiotics and endobiotics to more water-soluble compounds. The UDP …