The identification of the first mobile colistin resistance (MCR) gene, mcr-1, in 2015 triggered
a rash of mcr screening reports. Subsequently, nine MCR-family genes and their variants …

Following their initial discovery in the 1940s, polymyxin antibiotics fell into disfavor due to
their potential clinical toxicity, especially nephrotoxicity. However, the dry antibiotic …

The presence of bacteria carrying antimicrobial resistance (AMR) genes in wildlife is an
indicator that resistant bacteria of human or livestock origin are widespread in the …

Background Mobile colistin resistance (mcr) genes modify Lipid A molecules of the
lipopolysaccharide, changing the overall charge of the outer membrane. Results and …

Colistin is an old antimicrobial that has been revitalized as last-resort treatment against
multidrug-resistant (MDR) gram-negative bacterial infections. However, colistin has been …

Extended-spectrum beta-lactamase (ESBL)-producing Escherichia coli cause severe health
hazards. Migratory birds are reservoirs and transmitters of many pathogens including ESBL …

Antimicrobial resistance (AMR) is one of the most important global health concerns;
therefore, the identification of AMR reservoirs and vectors is essential. Attention should be …

The aquatic environment is a hotspot for the transfer of antibiotic resistance to humans and
animals. Several reviews have put together research efforts on the presence and distribution …

Antimicrobial resistance (AMR) is a current public health issue globally. To counter this
phenomenon and prioritize AMR in the health sector, the World Health Organization (WHO) …

Extended-spectrum beta-lactamase-producing Escherichia coli (ESBL-E. coli) have been
reported in wildlife worldwide. Whether wildlife is a transient host of ESBL-E. coli or …