Epidemiology of mobile colistin resistance genes mcr-1 to mcr-9

Z Ling, W Yin, Z Shen, Y Wang, J Shen… - Journal of …, 2020 - academic.oup.com
The identification of the first mobile colistin resistance (MCR) gene, mcr-1, in 2015 triggered
a rash of mcr screening reports. Subsequently, nine MCR-family genes and their variants …

[HTML][HTML] Occurrence and Characteristics of Mobile Colistin Resistance (mcr) Gene-Containing Isolates from the Environment: A Review

MU Anyanwu, IF Jaja, OC Nwobi - International journal of environmental …, 2020 - mdpi.com
The emergence and spread of mobile colistin (COL) resistance (mcr) genes jeopardize the
efficacy of COL, a last resort antibiotic for treating deadly infections. COL has been used in …

Antibiotic resistance genes in river biofilms: a metagenomic approach toward the identification of sources and candidate hosts

D Kneis, TU Berendonk, SK Forslund… - … Science & Technology, 2022 - ACS Publications
Treated wastewater is a major pathway by which antibiotic resistance genes (ARG) enter
aquatic ecosystems. However, knowledge gaps remain concerning the dissemination of …

[HTML][HTML] Correlation between exogenous compounds and the horizontal transfer of plasmid-borne antibiotic resistance genes

Y Liu, Z Tong, J Shi, Y Jia, K Yang, Z Wang - Microorganisms, 2020 - mdpi.com
The global spread of antibiotic resistance has posed a serious threat to public healthcare
and undermined decades of progress made in the fight against bacterial infections. It has …

Winter is coming–Impact of temperature on the variation of beta-lactamase and mcr genes in a wastewater treatment plant

L Schages, F Wichern, R Kalscheuer… - Science of the total …, 2020 - Elsevier
Wastewater treatment plants (WWTP) play a key role in the dissemination of antibiotic
resistance and analyzing the abundance of antibiotic resistance genes (ARGs) and resistant …

[HTML][HTML] Colistin-Resistant Enterobacteriaceae Isolated From Process Waters and Wastewater From German Poultry and Pig Slaughterhouses

M Savin, G Bierbaum, K Blau, M Parcina, E Sib… - Frontiers in …, 2020 - frontiersin.org
Due to the high prevalence of colistin-resistant Enterobacteriaceae in poultry and pigs,
process waters and wastewater from slaughterhouses were considered as a hotspot for …

[HTML][HTML] Epidemiology of mobile colistin resistance (mcr) genes in aquatic environments

Z Cherak, L Loucif, A Moussi, JM Rolain - Journal of Global Antimicrobial …, 2021 - Elsevier
Colistin is one of the last-line therapies against multidrug-resistant Gram-negative
pathogens, especially carbapenemase-producing isolates, making resistance to this …

What is the role of the environment in the emergence of novel antibiotic resistance genes? A modeling approach

J Bengtsson-Palme, V Jonsson… - Environmental Science & …, 2021 - ACS Publications
It is generally accepted that intervention strategies to curb antibiotic resistance cannot solely
focus on human and veterinary medicine but must also consider environmental settings …

Knowledge gaps in the assessment of antimicrobial resistance in surface waters

M Niegowska, I Sanseverino, A Navarro… - FEMS Microbiology …, 2021 - academic.oup.com
The spread of antibiotic resistance in the water environment has been widely described.
However, still many knowledge gaps exist regarding the selection pressure from antibiotics …

Slaughterhouse wastewater as a reservoir for extended-spectrum β-lactamase (ESBL)-producing, and colistin-resistant Klebsiella spp. and their impact in a “One …

M Savin, G Bierbaum, RM Schmithausen… - Science of The Total …, 2022 - Elsevier
Klebsiella spp. are ubiquitous bacteria capable of colonizing humans and animals, and
sometimes leading to severe infections in both. Due to their high adaptability against …