The functionalization of C (sp3)− H bonds streamlines chemical synthesis by allowing the
use of simple molecules and providing novel synthetic disconnections. Intensive recent …

Sulfoximines are widely used as medicines, agricultural chemicals, chiral precursors, and
chiral ligands in asymmetric synthesis, as well as pivotal intermediates for the construction of …

Allylic amines are valuable synthetic targets en route to diverse biologically active amine
products. Current allylic C–H amination strategies remain limited with respect to the viable N …

A key aspect of bacterial survival is the ability to evolve while migrating across spatially
varying environmental challenges. Laboratory experiments, however, often study evolution …

Primary and N-alkyl arylamine motifs are key functional groups in pharmaceuticals,
agrochemicals, and functional materials, as well as in bioactive natural products. However …

A new system for NH transfer is developed for the preparation of sulfoximines, which are
emerging as valuable motifs for drug discovery. The protocol employs readily available …

Allylic C–H amination is currently accomplished with (sulfon) amides or carbamates. Here
we show the first allylic amination that can directly afford alkyl allylamines, enabled by the …

Experimental, spectroscopic, and computational studies are reported that provide an
evidence-based mechanistic description of an intermolecular reductive C–N coupling of …

The synthesis of aromatic amines is of utmost importance in a wide range of chemical
contexts. We report a direct amination of boronic acids with nitro compounds to yield (hetero) …

The development of efficient catalytic methods for N–C bond cleavage in amides remains an
important synthetic challenge. The first Pd-catalyzed Suzuki–Miyaura cross-coupling of N …