Abstract 'Reactive oxygen species'(ROS) is a generic term that defines a wide variety of
oxidant molecules with vastly different properties and biological functions that range from …

Abstract The European Cooperation in Science and Technology (COST) provides an ideal
framework to establish multi-disciplinary research networks. COST Action BM1203 (EU …

Dormant hematopoietic stem cells (dHSCs) are atop the hematopoietic hierarchy. The
molecular identity of dHSCs and the mechanisms regulating their maintenance or exit from …

Reactive oxygen species (ROS) act as intracellular compartmentalized second messengers,
mediating metabolic stress-adaptation. In skeletal muscle fibers, ROS have been suggested …

Hematopoietic stem cells (HSCs) rely on complex regulatory networks to preserve stemness.
Due to the scarcity of HSCs, technical challenges have limited our insights into the interplay …

Skeletal muscle has long been recognized as an inhospitable site for disseminated tumour
cells (DTCs). Yet its antimetastatic nature has eluded a thorough mechanistic examination …

Cellular redox homeostasis is an essential, dynamic process that ensures the balance
between reducing and oxidizing reactions within cells and thus has implications across all …

Immune cells must adapt to different environments during the course of an immune
response. Here we study the adaptation of CD8+ T cells to the intestinal microenvironment …

Pancreatic islet transplantation still represents a promising therapeutic strategy for curative
treatment of type 1 diabetes mellitus. However, a limited number of organ donors and …

Key message Pollen heat acclimation. Abstract As a consequence of global warming, plants
have to face more severe and more frequently occurring periods of high temperature stress …