Abstract Our previous International Union of Basic and Clinical Pharmacology report on the
nomenclature and classification of adenosine receptors (2011) contained a number of …

A great deal of experimental evidence suggests that ligands can stabilize different receptor
active states that go on to interact with cellular signaling proteins to form a range of different …

Adenosine receptors (ARs) function in the body's response to conditions of pathology and
stress associated with a functional imbalance, such as in the supply and demand of …

As an endogenous neuroprotectant agent, adenosine is extensively distributed and is
particularly abundant in the central nervous system (CNS). Under physiological conditions …

Introduction Adaptogens are natural compounds or plant extracts that increase adaptability
and survival of organisms under stress. Adaptogens stimulate cellular and organismal …

Epilepsy is one of the most serious and common chronic neurological conditions,
characterised by recurrent hypersynchronous electrical activity in the brain that lead to …

Many central biological events rely on protein–ligand interactions. The identification and
characterization of protein-binding sites for ligands are crucial for the understanding of …

Abstract Cannabinoid receptors type 1 (CB 1) and type 2 (CB 2) are promising targets for a
number of diseases, including obesity, neuropathic pain, and multiple sclerosis, among …

Prostaglandin receptors have been implicated in a wide range of functions, including
inflammation, immune response, reproduction, and cancer. Our group has previously …

The discovery and clinical implementation of modulators of adenosine, P2Y and P2X
receptors (comprising nineteen subtypes) have progressed dramatically in∼ 50 years since …