A three-dimensional (3D) organotypic microfluidic model for glioma stem cells–Vascular interactions

D Truong, R Fiorelli, ES Barrientos, EL Melendez… - Biomaterials, 2019 - Elsevier
Glioblastoma (GBM) is one of the deadliest forms of cancer. Despite many treatment options,
prognosis of GBM remains dismal with a 5-year survival rate of 4.7%. Even then, tumors …

DFT Study of Molecular Stability and Reactivity on Some Hydroxamic Acids: An Approach by Hirshfeld Population Analysis

D Soro, L Ekou, MGR Koné, T Ekou… - European Journal of …, 2019 - ej-eng.org
Several studies have been carried out on the structure of hydroxamic acids as histone
deacetylase inhibitors. Scientists discovered that the (-CONHOH) moiety of hydroxamic …

Engineering of a novel breast tumor microenvironment on a microfluidic chip

M Nikkhah, D Truong - US Patent 10,712,339, 2020 - Google Patents
A microfluidic device for more accurately modeling the in vitro environment in which cancer
occurs is disclosed. The microfluidic device includes a surface defining one or more …