[HTML][HTML] Osteopontin, a bridge links osteoarthritis and osteoporosis
RJ Bai, YS Li, FJ Zhang - Frontiers in Endocrinology, 2022 - frontiersin.org
Osteoarthritis (OA) is the most prevalent joint disease characterized by degradation of
articular cartilage, inflammation, and changes in periarticular and subchondral bone of …
articular cartilage, inflammation, and changes in periarticular and subchondral bone of …
[HTML][HTML] Osteopontin: a bone-derived protein involved in rheumatoid arthritis and osteoarthritis immunopathology
BT Martín-Márquez, F Sandoval-García… - Biomolecules, 2023 - mdpi.com
Osteopontin (OPN) is a bone-derived phosphoglycoprotein related to physiological and
pathological mechanisms that nowadays has gained relevance due to its role in the immune …
pathological mechanisms that nowadays has gained relevance due to its role in the immune …
Association of osteopontin with osteoarthritis
C Cheng, S Gao, G Lei - Rheumatology international, 2014 - Springer
The joint disease osteoarthritis (OA) is the most common form of arthritis, which mainly
affects the older people. OA is becoming one of the major non-fatal health burdens of the …
affects the older people. OA is becoming one of the major non-fatal health burdens of the …
[HTML][HTML] Extracellular calcium ion concentration regulates chondrocyte elastic modulus and adhesion behavior
Extracellular calcium ion concentration levels increase in human osteoarthritic (OA) joints
and contribute to OA pathogenesis. Given the fact that OA is a mechanical problem, the …
and contribute to OA pathogenesis. Given the fact that OA is a mechanical problem, the …
OPN deficiency increases the severity of osteoarthritis associated with aberrant chondrocyte senescence and apoptosis and upregulates the expression of …
J Tian, C Cheng, SD Kuang, C Su… - Pain Research and …, 2020 - Wiley Online Library
Objectives. A recent work has reported that the elevated osteopontin (OPN) levels in the
articular cartilage and synovial fluid are correlated with the progressive osteoarthritis (OA) …
articular cartilage and synovial fluid are correlated with the progressive osteoarthritis (OA) …
Synovia tissue-specific exosomes participate in the dual variation of the osteoarthritis microenvironment via miR-182
S Wu, J Luo, X Zhang, L Wang, L Cai, J Xu - Experimental Cell Research, 2024 - Elsevier
Osteoarthritis (OA) is the most common type of joint disease and the leading cause of
chronic disability among older adults. As an important component of the joint, synovium …
chronic disability among older adults. As an important component of the joint, synovium …
Menisectomized miniature Vietnamese pigs develop articular cartilage pathology resembling osteoarthritis
R Cruz, C Ramírez, OI Rojas, O Casas-Mejía… - … -Research and Practice, 2015 - Elsevier
Animal models have been used to understand the basic biology of osteoarthritis (OA) and
have helped to identify new candidate biomarkers for the early diagnosis and treatment of …
have helped to identify new candidate biomarkers for the early diagnosis and treatment of …
[HTML][HTML] Proteomic analysis of rat cartilage: the identification of differentially expressed proteins in the early stages of osteoarthritis
NM Parra-Torres, FE Cázares-Raga, JB Kouri - Proteome science, 2014 - Springer
Background Osteoarthritis (OA) is a chronic degenerative disease of the articular cartilage,
and its diagnosis is based on symptoms and radiological signs that are only present in the …
and its diagnosis is based on symptoms and radiological signs that are only present in the …
[HTML][HTML] Phosphorylation of osteopontin has proapoptotic and proinflammatory effects on human knee osteoarthritis chondrocytes
SG Gao, Y Yu, C Zeng, ST Lu… - Experimental and …, 2016 - spandidos-publications.com
The aim of the present study was to investigate the effects of phosphorylated osteopontin (p-
OPN) on apoptosis and pro-inflammatory cytokine expression in human knee osteoarthritis …
OPN) on apoptosis and pro-inflammatory cytokine expression in human knee osteoarthritis …
[HTML][HTML] 骨桥蛋白干预体外培养人膝骨关节炎软骨细胞蛋白多糖和Ⅱ 型胶原的表达
朱鹤远, 雷光华, 高曙光, 张方杰, 曾超, 张凯 - 中国组织工程研究, 2016 - cjter.com
骨桥蛋白干预体外培养人膝骨关节炎软骨细胞蛋白多糖和Ⅱ型胶原的表达 中国组织工程研究
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