The repositioning or “repurposing” of existing therapies for alternative disease indications is
an attractive approach that can save significant investments of time and money during drug …

Hepatocellular carcinoma (HCC) is an aggressive tumor with a poor prognosis. Currently,
only sorafenib is approved by the FDA for advanced HCC treatment; therefore, there is an …

Purpose The etiology of nasopharyngeal carcinoma (NPC) is multifactorial, complex and not
fully characterized yet. MicroRNAs (miRNAs or miRs) have been found to contribute to the …

Objective Nasopharyngeal carcinoma (NPC) is a rare malignancy in most parts of the world,
but is a common cancer in southern Asia. Local recurrent disease and distant metastasis of …

Introduction Nasopharyngeal carcinoma (NPC) is a common cancer in southern China and
Taiwan, and radiation therapy combined with or without chemotherapy is its mainstay …

Background Abnormal proliferation of vascular smooth muscle cells (VSMC) is a major
cause of cardiovascular diseases (CVDs). Many studies suggest that vascular injury triggers …

PG2 is a botanical drug that is mostly composed of Astragalus polysaccharides (APS). Its
role in hematopoiesis and relieving cancer‐related fatigue has recently been clinically …

Introduction. The role of podoplanin (PDPN) in nasopharyngeal carcinoma (NPC) is still
unknown. The aims of this study were to investigate the expression and role of PDPN in …

Background Trifluoperazine (TFP) is a typical antipsychotic primarily used to treat
schizophrenia. In this study, we aimed to evaluate whether TFP can be used as a …

Lung cancer is one of the leading causes of death in both the USA and Taiwan, and it is
thought that the cause of cancer could be because of the gain of function of an oncoprotein …