Homogeneous catalytic hydrogenation has played an important role in the development of
modern organic synthesis. Indeed, the discovery of highly regio-and stereoselective …

Understanding olfaction at the molecular level is challenging due to the lack of
crystallographic models of odorant receptors (ORs). To better understand the molecular …

We describe herein the development of the first iridium‐catalyzed allylic substitution using
arylzinc nucleophiles. High enantioselectivities were obtained from the reactions, which …

A combination of X-ray crystallography, 6Li, 15N, and 13C NMR spectroscopies, and density
functional theory computations affords insight into the structures and reactivities of …

Iridium-Catalyzed Asymmetric Allylic Substitution with Aryl Zinc Reagents | Organic Letters ACS
ACS Publications C&EN CAS Find my institution Log In Organic Letters ACS Publications. Most …

The difluoromethylene (CF2) group has a strong tendency to adopt corner over edge
locations in aliphatic macrocycles. In this study, the CF2 group has been introduced into …

The exocyclically unsaturated conjugated keto esters 10, obtained via a Claisen ortho ester
rearrangement of the allylic hydroxy ketones 9, were either directly hydrogenated or partially …

Enoates derived from α− substituted acrylates containing 3-pyrazolidinone achiral template
with Brønsted basic fluxional substituents were evaluated in chiral Lewis acid catalyzed …

Two alternative methods for the synthesis of (9E)-isoambrettolide are established via the
rapid lactonization of the free threo-aleuritic acid or its protected seco-acid using substituted …

A combination of 1H, 6Li, 13C, and 15N NMR spectroscopies and density functional theory
computations explores the formation of mixed aggregates by a dilithium salt of a C2 …