Diabetes is a chronic and progressive syndrome commonly associated with several
neuropsychiatric comorbities, of which depression is the most studied. The prevalence of …

Abstract Type 2 diabetes (T2D) is a metabolic disease caused by the development of insulin
resistance (IR), relative insulin deficiency, and hyperglycemia. Hyperglycemia-induced …

In the pancreatic islet, serotonin is an autocrine signal increasing beta cell mass during
metabolic challenges such as those associated with pregnancy or high-fat diet. It is still …

In the past few years possible mechanisms that link diabetes and depression have been
found. One of these mechanisms is the increase in lipid peroxidation and decrease in …

Aim This study investigated whether therapeutically relevant concentrations of fluoxetine,
which have been shown to reduce plasma glucose and glycated haemoglobin independent …

Life-threatening hypoglycemia is a limiting factor in the management of type 1 diabetes.
People with diabetes are prone to develop hypoglycemia because they lose physiological …

CYP2D6 and CYP2C19 enzymes are essential in the metabolism of antidepressants and
antipsychotics. Genetic variation in these genes may increase risk of adverse drug reactions …

Objectives The metabolic effects of antidepressants should be considered when prescribing
antidepressants due to the increasing risk of diabetes, obesity and cardiovascular disease …

Diabetes mellitus is a chronic disease that is associated with depression. Also, depression is
common in adults with type 2 diabetes mellitus (T2DM). Translocator protein (18kDa)(TSPO) …

Background: Drugs and alcohol are the commonest causes of hypoglycaemia and account
for a significant number of emergency department attendances and hospital admissions …