Acute inflammation or resolved inflammation is an adaptive host defense mechanism and is
self-limiting, which returns the body to a state of homeostasis. However, unresolved …

Simple Summary This review describes in a very detailed and exhaustive approach the
literature of these last 20 years on glioblastoma targeted therapies in Phases II-IV of 257 …

Human malignancies are one of the major health-related issues though out the world and
anticipated to rise in the future. The development of novel drugs/agents requires a huge …

WNTs and their downstream effectors regulate proliferation, death, and migration and cell
fate decision. Deregulation of WNT signaling is associated with various cancers including …

Glioblastoma multiforme (GBM) is among the most incurable cancers. GBMs survival rate
has not markedly improved, despite new radical surgery protocols, the introduction of new …

The Wnt/β-catenin signaling pathway is a growth control pathway involved in various
biological processes as well as the development and progression of cancer. Colorectal …

Colorectal cancer (CRC) is one of the most common malignant tumor types occurring in the
digestive system. The incidence of CRC has exhibits yearly increases and the mortality rate …

Wnt signaling plays an essential role in the initiation and progression of various types of
cancer. Besides, the Wnt pathway components have been established as reliable …

Curcumin, also known as diferuloylmethane, is the main polyphenolic substance present in
the rhizomes of Curcuma longa L. This plant showed many beneficial effects and has been …

Diclofenac (DCF) is a well-known and widely used non-steroidal anti-inflammatory drug
(NSAID), with a range of actions which are of interest in an oncological context. While there …