CXCL1 is one of the most important chemokines, part of a group of chemotactic cytokines
involved in the development of many inflammatory diseases. It activates CXCR2 and, at high …

Background: Worldwide, lung cancer is one of the leading causes of cancer death.
Nevertheless, new therapeutic agents have been developed to treat lung cancer that could …

Although labile iron plays critical roles in diverse biological processes in living cells, the
physiological and pathophysiological functions of iron have not been sufficiently explored …

Iron oxide nanoparticles (ION) with superparamagnetic properties hold great promise for use
in various biomedical applications; specific examples include use as contrast agents for …

Anemia in β-thalassemia is related to ineffective erythropoiesis and reduced red cell
survival. Excess free heme and accumulation of unpaired α-globin chains impose …

Iron is an essential element for life on earth, participating in a plethora of cellular processes
where one-electron transfer reactions are required. Its essentiality, coupled to its scarcity in …

Iron (Fe) species play a number of biologically and pathologically important roles. In
particular, iron is a key element in oxygen sensing in living tissue where its metabolism is …

Iron is essential for life, but excess iron can be toxic. As a potent free radical creator, iron
generates hydroxyl radicals leading to significant oxidative stress. Since iron is not excreted …

The accumulation of transition metals (eg, copper, zinc, and iron) and the dysregulation of
their metabolism are a hallmark in the pathogenesis of several neurodegenerative diseases …

Objective. Cervical cancer (CC) is a prevalent cancer in women. Hypoxia plays a critical role
in CC cell ferroptosis resistance. This study explored the mechanism of hypoxia in CC cell …