MIC-1/GDF15 is a stress response cytokine and a distant member of the transforming growth
factor beta (TGFb) superfamily, with no close relatives. It acts via a recently identified …

Abstract GDF-15 (also MIC-1, NAG-1, PLAB, PTGFB) is a member of the TGF-β superfamily,
which is widely distributed in mammalian tissues and has been shown to play multiple roles …

BACKGROUND Growth differentiation factor 15 (GDF-15) is emerging as a powerful risk
indicator in both cardiovascular disease patients and community-dwelling individuals. We …

Background We investigated whether circulating concentrations of soluble ST2, growth
differentiation factor–15 (GDF-15), and high-sensitivity troponin I (hsTnI) are associated with …

Abstract Growth differentiation factor-15 (GDF-15), also known as macrophage inhibitory
cytokine-1 (MIC-1) or non-steroidal anti-inflammatory drug-activated gene (NAG-1) has been …

Background and Purpose—Growth differentiation factor-15 (GDF-15) and soluble (s) ST2
are markers of cardiac and vascular stress. We investigated the associations between …

Brain disorders, such as Alzheimer's and Parkinson's disease and cerebral stroke, are an
important contributor to mortality and disability worldwide, where their pathogenesis is …

Vascular pathology plays an important role in the development of cognitive decline and
dementia. In this context, growth differentiation factor-15 (GDF-15) has been suggested to be …

680 Stroke February 2020 developed cardiovascular events including AMI and acute HF.
These cardiovascular events occurred more frequently in patients with a recent history of …

From the available findings, MIC-1/GDF15 can be considered as a marker of age-related
cognitive decline and brain structural changes. Combining MIC-1/GDF15 with other …