Characterization and culture of human embryonic stem cells

LM Hoffman, MK Carpenter - Nature biotechnology, 2005 - nature.com
Human embryonic stem cells have been defined as self-renewing cells that can give rise to
many types of cells of the body. How and whether these cells can be manipulated to replace …

Hurdles to clinical translation of human induced pluripotent stem cells

E Neofytou, CG O'Brien, LA Couture… - The Journal of clinical …, 2015 - Am Soc Clin Investig
Human pluripotent stem cells are known to have the capacity to renew indefinitely, being
intrinsically able to differentiate into many different cell types. These characteristics have …

Human embryonic stem cell–derived CD34+ cells: efficient production in the coculture with OP9 stromal cells and analysis of lymphohematopoietic potential

MA Vodyanik, JA Bork, JA Thomson, II Slukvin - Blood, 2005 - ashpublications.org
Embryonic stem (ES) cells have the potential to serve as an alternative source of
hematopoietic precursors for transplantation and for the study of hematopoietic cell …

A new population of human adult dental pulp stem cells: a useful source of living autologous fibrous bone tissue (LAB)

G Laino, R d'Aquino, A Graziano… - Journal of bone and …, 2005 - academic.oup.com
Stem cells, derived from human adult dental pulp of healthy subjects 30‐45 years of age,
were cultured, and cells were selected using a FACSorter. A new c‐kit+/CD34+/CD45− cell …

Human-induced pluripotent stem cells from blood cells of healthy donors and patients with acquired blood disorders

Z Ye, H Zhan, P Mali, S Dowey… - Blood, The Journal …, 2009 - ashpublications.org
Human induced pluripotent stem (iPS) cells derived from somatic cells hold promise to
develop novel patient-specific cell therapies and research models for inherited and acquired …

HLA engineering of human pluripotent stem cells

L Riolobos, RK Hirata, CJ Turtle, PR Wang… - Molecular Therapy, 2013 - cell.com
The clinical use of human pluripotent stem cells and their derivatives is limited by the
rejection of transplanted cells due to differences in their human leukocyte antigen (HLA) …

Banking on human embryonic stem cells: estimating the number of donor cell lines needed for HLA matching

CJ Taylor, EM Bolton, S Pocock, LD Sharples… - The Lancet, 2005 - thelancet.com
Background Human embryonic stem (hES) cells are a promising source for transplantation
to replace diseased or damaged tissue, but their differentiated progeny express human …

Human embryonic stem cells and their differentiated derivatives are less susceptible to immune rejection than adult cells

M Drukker, H Katchman, G Katz… - Stem …, 2006 - academic.oup.com
Differentiated cell types derived from human embryonic stem cells (hESCs) may serve in the
future to treat various human diseases. A crucial step toward their successful clinical …

An approachable human adult stem cell source for hard‐tissue engineering

G Laino, A Graziano, R d'Aquino… - Journal of cellular …, 2006 - Wiley Online Library
Stem cells were obtained from deciduous dental pulp of healthy subjects, aged 6–10 years.
This stem cell population was cultured, expanded, and specifically selected, detecting using …

Improved efficiency and pace of generating induced pluripotent stem cells from human adult and fetal fibroblasts

P Mali, Z Ye, HH Hommond, X Yu, J Lin, G Chen… - Stem …, 2008 - academic.oup.com
It was reported recently that human fibroblasts can be reprogrammed into a pluripotent state
that resembles that of human embryonic stem (hES) cells. This was achieved by ectopic …