Genetics of adult glioma

MKL Goodenberger, RB Jenkins - Cancer genetics, 2012 - Elsevier
Gliomas make up approximately 30% of all brain and central nervous system tumors and
80% of all malignant brain tumors. Despite the frequency of gliomas, the etiology of these …

MicroRNAs in body fluids—the mix of hormones and biomarkers

MA Cortez, C Bueso-Ramos, J Ferdin… - Nature reviews Clinical …, 2011 - nature.com
Since the discovery of microRNAs (miRNAs), the study of these small noncoding RNAs has
steadily increased and more than 10,000 papers have already been published. The great …

Genetic variation in microRNA networks: the implications for cancer research

BM Ryan, AI Robles, CC Harris - Nature reviews cancer, 2010 - nature.com
Many studies have highlighted the role that microRNAs have in physiological processes and
how their deregulation can lead to cancer. More recently, it has been proposed that the …

[HTML][HTML] Semi-supervised learning for potential human microRNA-disease associations inference

X Chen, GY Yan - Scientific reports, 2014 - nature.com
MicroRNAs play critical role in the development and progression of various diseases.
Predicting potential miRNA-disease associations from vast amount of biological data is an …

The role of microRNAs in human diseases

KU Tüfekci, MG Öner, RLJ Meuwissen… - … : MicroRNA biology and …, 2014 - Springer
About 20 years have passed since the discovery of the first microRNA (miRNA) and by now
microRNAs are implicated in a variety of physiological and pathological processes. Since …

Aberrant expression of microRNAs in bladder cancer

H Yoshino, N Seki, T Itesako, T Chiyomaru… - Nature Reviews …, 2013 - nature.com
MicroRNAs (miRNAs), a class of small noncoding RNAs, regulate protein-coding gene
expression by repressing translation or cleaving RNA transcripts in a sequence-specific …

[HTML][HTML] RBMMMDA: predicting multiple types of disease-microRNA associations

X Chen, C Clarence Yan, X Zhang, Z Li, L Deng… - Scientific reports, 2015 - nature.com
Accumulating evidences have shown that plenty of miRNAs play fundamental and important
roles in various biological processes and the deregulations of miRNAs are associated with a …

MicroRNA target site polymorphisms and human disease

P Sethupathy, FS Collins - Trends in genetics, 2008 - cell.com
MicroRNAs (miRNAs) are important regulators of eukaryotic gene expression. They have
been implicated in a broad range of biological processes, and miRNA-related genetic …

MicroRNA polymorphisms: the future of pharmacogenomics, molecular epidemiology and individualized medicine

PJ Mishra, JR Bertino - Pharmacogenomics, 2009 - Taylor & Francis
Referred to as the micromanagers of gene expression, microRNAs (miRNAs) are
evolutionarily conserved small noncoding RNAs. Polymorphisms in the miRNA pathway …

Robust strand exchange reactions for the sequence-specific, real-time detection of nucleic acid amplicons

YS Jiang, S Bhadra, B Li, YR Wu, JN Milligan… - Analytical …, 2015 - ACS Publications
Loop-mediated isothermal amplification (LAMP) of DNA is a powerful isothermal nucleic
acid amplification method that can generate upward of 109 copies from less than 100 copies …