Abstract The coronavirus disease 2019 (COVID-19) pandemic has affected the mental
health of individuals worldwide, and the risk of psychiatric sequelae and consequent mental …

on understanding the complexity of central immune cells and peripheral immune cells, and
their cross-talk mechanisms in diverse CNS pathologies. Eleven peer-reviewed manuscripts …

RNA splicing is a post-transcriptional event that regulates many physiological and
pathological events. However, whether RNA splicing regulates cerebral I/R-induced brain …

Anti-Leucine-rich glioma inactivated-1 (LGI1) and anti-contactin-associated-protein-2
(CASPR2) associated autoimmune encephalitis (AIE) variants are characterized by directly …

In recent years, increasing evidence has highlighted the critical role of myeloid cells,
specifically those that present antigen (APCs) in health and disease. These shape the …

Background T cells have been implicated in various neurological conditions, yet their role in
neonatal brain injuries remains unclear. This study aimed to investigate the impact of …

Objective While observational studies link immune cells with post-stroke functional outcome,
the underlying immune mechanisms are not well understood. Immune cell surface antigens …

We reported that a 31-amino-acid Zfra protein (z inc f inger-like protein that r egulates a
poptosis) blocks neurodegeneration and cancer growth. Zfra binds WW domain-containing …

Background In its tetrameric form, pyruvate kinase M2 isoform (PKM2) catalyzes the last step
of glycolysis and plays a key role in the metabolic reprogramming via regulating the …

The process of aging is accompanied by a dynamic restructuring of the immune response, a
phenomenon known as immunosenescence. Further, damage to the endothelium can be …