The innate immune system is the first line of host defense against infection and is comprised
of humoral and cellular mechanisms that recognize potential pathogens within minutes or …

Innate recognition of virus proteins is an important component of the immune response to
viral pathogens. A component of this immune recognition is the family of lectins; pattern …

In the innate immune system, a variety of recognition molecules provide the first-line host
defense to prevent infection and maintain endogenous homeostasis. Ficolin is a soluble …

Human L‐ficolin (P35, ficolin‐2) is synthesised in the liver and secreted into the bloodstream
where it is one of the major pattern recognition molecules of plasma/serum. Like other …

Ficolins are innate pattern recognition receptors (PRR) and play integral roles within the
innate immune response to numerous pathogens throughout the circulation, as well as …

Rapid and efficient methods for the determination of cured tuberculosis (TB) are lacking. A
total of 85 differentially expressed serum proteins were identified by iTRAQ labeling coupled …

Background L-ficolin (encoded by FCN2) binds to acetylated sugar moieties of many
pathogens, including Trypanosoma cruzi, promoting their phagocytosis and lysis by the …

The complement system plays multiple roles in host defense against infection and is
supposed to confer genetic susceptibility to leprosy. We aimed to examine whether genetic …

Human Ficolin-2 (L-ficolins) encoded by FCN2 gene is a soluble serum protein that plays an
important role in innate immunity and is mainly expressed in the liver. Ficolin-2 serum levels …

Abstract Background. Human ficolin-2 (L-ficolins) encoded by the FCN2 gene are pattern-
recognition proteins involved in innate immunity and are associated with several infectious …