Further developments and applications of oxazoline-containing ligands in asymmetric catalysis

R Connon, B Roche, BV Rokade, PJ Guiry - Chemical Reviews, 2021 - ACS Publications
The chiral oxazoline motif is present in many ligands that have been extensively applied in a
series of important metal-catalyzed enantioselective reactions. This Review aims to provide …

Influenza neuraminidase inhibitors: synthetic approaches, derivatives and biological activity

P Laborda, SY Wang, J Voglmeir - Molecules, 2016 - mdpi.com
Despite being a common viral disease, influenza has very negative consequences, causing
the death of around half a million people each year. A neuraminidase located on the surface …

Recent Developments in Enantioselective Metal‐Catalyzed Domino Reactions

H Pellissier - Advanced Synthesis & Catalysis, 2016 - Wiley Online Library
This review updates the major progress in the field of enantioselective one‐, two‐, and multi‐
component domino reactions promoted by chiral metal catalysts, covering the literature …

Catalytic asymmetric Friedel–Crafts alkylation of unprotected indoles with nitroalkenes using a novel chiral Yb(OTf)3–pybox complex

B Karimi, E Jafari, F Mansouri, M Tavakolian - Scientific Reports, 2023 - nature.com
Chiral chloro-indeno pybox has served as a new ligand for the Yb (OTf) 3-catalyzed
asymmetric Friedel–Crafts alkylation reaction of indoles with nitroalkenes. The tunable …

Fast, solvent-free, highly enantioselective three-component coupling of aldehydes, alkynes, and amines catalysed by the copper (II) pybox complex under high …

Z Li, Z Jiang, W Su - Green Chemistry, 2015 - pubs.rsc.org
Chiral propargylamines were synthesized in good to excellent yields with high
enantioselectivity via Cu (OTf) 2/Ph-Pybox catalysed, solvent-free three-component …

The evolution of Tamiflu synthesis, 20 years on: Advent of enabling technologies the last piece of the puzzle?

CR Sagandira, FM Mathe, U Guyo, P Watts - Tetrahedron, 2020 - Elsevier
Influenza is a serious respiratory disease responsible for significant morbidity and mortality
due to both annual epidemics and pandemics; its treatment involves the use of …

Asymmetric alkynylation of seven-membered cyclic imines by combining chiral phosphoric acids and Ag (I) catalysts: synthesis of 11-substituted-10, 11 …

YY Ren, YQ Wang, S Liu - The Journal of Organic Chemistry, 2014 - ACS Publications
Asymmetric alkynylation of seven-membered cyclic imine dibenzo [b, f][1, 4] oxazepines is
successfully achieved by combining chiral phosphoric acid and Ag (I) catalysts. Various …

Recent advances in the transformations of cycloalkane-fused oxiranes and aziridines

M Nonn, AM Remete, F Fülöp, L Kiss - Tetrahedron, 2017 - Elsevier
This account highlights the most relevant transformations of cycloalkane-fused oxiranes and
aziridines developed during the past decade with the intention to provide an overview of the …

Efficient Synthesis of N‐Alkylated 4‐Pyridones by Copper‐Catalyzed Intermolecular Asymmetric Propargylic Amination

W Shao, Y Wang, ZP Yang, X Zhang… - Chemistry–An Asian …, 2018 - Wiley Online Library
Copper‐catalyzed intermolecular asymmetric propargylic amination with 4‐hydroxypyridines
has been realized for the first time. In the presence of Cu complex derived from Pybox …

Syntheses of natural and biologically relevant products through asymmetric metal-catalyzed domino reactions. A review

H Pellissier - Organic Preparations and Procedures International, 2019 - Taylor & Francis
A challenging goal in synthetic chemistry is the synthesis of complex products from simple
starting materials by using one-step processes such as domino reactions. 1–16 A domino …