Diverse repertoire of human adipocyte subtypes develops from transcriptionally distinct mesenchymal progenitor cells
Single-cell sequencing technologies have revealed an unexpectedly broad repertoire of
cells required to mediate complex functions in multicellular organisms. Despite the multiple …
cells required to mediate complex functions in multicellular organisms. Despite the multiple …
Characterization of transcript enrichment and detection bias in single-nucleus RNA-seq for mapping of distinct human adipocyte lineages
Single-cell RNA sequencing (scRNA-seq) enables molecular characterization of complex
biological tissues at high resolution. The requirement of single-cell extraction, however …
biological tissues at high resolution. The requirement of single-cell extraction, however …
Bone morphogenetic protein 2 is a depot-specific regulator of human adipogenesis
NF Denton, M Eghleilib, S Al-Sharifi… - International journal of …, 2019 - nature.com
Abstract Background Bone morphogenetic proteins (BMPs) regulate adipogenesis but it is
not clear whether they influence regional adipose tissue (AT) development in humans …
not clear whether they influence regional adipose tissue (AT) development in humans …
A novel role of Id1 in regulating oscillatory shear stress-mediated lipid uptake in endothelial cells
K Zhang, Y Chen, T Zhang, L Huang, Y Wang… - Annals of biomedical …, 2018 - Springer
Inhibitor of DNA binding 1 (Id1) has been shown to be involved in adipogenesis and
metabolism, which may contribute to atherosclerotic progression. However, it remains …
metabolism, which may contribute to atherosclerotic progression. However, it remains …
PGC1α cooperates with FOXA1 to regulate epithelial mesenchymal transition through the TCF4-TWIST1
XQ Fang, M Lee, WJ Lim, S Lee, CH Lim… - International journal of …, 2022 - mdpi.com
The peroxisome proliferator-activated receptor gamma coactivator 1-alpha (PGC1α) is a
critical transcriptional coactivator that maintains metabolic homeostasis and energy …
critical transcriptional coactivator that maintains metabolic homeostasis and energy …
[HTML][HTML] Noggin depletion in adipocytes promotes obesity in mice
AM Blázquez-Medela, M Jumabay, P Rajbhandari… - Molecular …, 2019 - Elsevier
Objective Obesity has increased to pandemic levels and enhanced understanding of
adipose regulation is required for new treatment strategies. Although bone morphogenetic …
adipose regulation is required for new treatment strategies. Although bone morphogenetic …
BMP7 increases UCP1-dependent and independent thermogenesis with a unique gene expression program in human neck area derived adipocytes
White adipocytes contribute to energy storage, accumulating lipid droplets, whereas brown
and beige adipocytes mainly function in dissipating energy as heat primarily via the action of …
and beige adipocytes mainly function in dissipating energy as heat primarily via the action of …
[HTML][HTML] 鸡脂肪组织TCF21基因启动子区DNA甲基化与其表达的关系
刘雨萌, 马艳艳, 姜海煦, 张心扬, 武春艳, 程博涵… - 畜牧兽医学报, 2021 - xml-data.org
旨在研究鸡脂肪组织中TCF21 基因启动子区DNA 甲基化水平与其表达的关系.
以东北农业大学高, 低腹脂双向选择品系(简称高, 低脂系) 第24 世代7 周龄肉鸡为试验材料 …
以东北农业大学高, 低腹脂双向选择品系(简称高, 低脂系) 第24 世代7 周龄肉鸡为试验材料 …
Multiple human adipocyte subtypes and mechanisms of their development
Human adipose tissue depots perform numerous diverse physiological functions, and are
differentially linked to metabolic disease risk, yet only two major human adipocyte subtypes …
differentially linked to metabolic disease risk, yet only two major human adipocyte subtypes …
Upregulation of Inhibitor of DNA Binding 1 and 3 is Important for Efficient Thermogenic Response in Human Adipocytes
Brown and beige adipocytes can be activated by β-adrenergic agonist via cAMP-dependent
signaling. Performing RNA-sequencing analysis in human cervical area-derived adipocytes …
signaling. Performing RNA-sequencing analysis in human cervical area-derived adipocytes …