[Retracted] Ellagic Acid: A Review on Its Natural Sources, Chemical Stability, and Therapeutic Potential

J Sharifi-Rad, C Quispe, CMS Castillo… - Oxidative medicine …, 2022 - Wiley Online Library
Ellagic acid (EA) is a bioactive polyphenolic compound naturally occurring as secondary
metabolite in many plant taxa. EA content is considerable in pomegranate (Punica granatum …

A pharmacological update of ellagic acid

JL Ríos, RM Giner, M Marín, MC Recio - Planta medica, 2018 - thieme-connect.com
Ellagic acid is a common metabolite present in many medicinal plants and vegetables. It is
present either in free form or as part of more complex molecules (ellagitannins), which can …

Possible mechanisms of oxidative stress-induced skin cellular senescence, inflammation, and cancer and the therapeutic potential of plant polyphenols

HM Liu, MY Cheng, MH Xun, ZW Zhao… - International Journal of …, 2023 - mdpi.com
As the greatest defense organ of the body, the skin is exposed to endogenous and external
stressors that produce reactive oxygen species (ROS). When the antioxidant system of the …

Ultraviolet radiation‐induced skin aging: the role of DNA damage and oxidative stress in epidermal stem cell damage mediated skin aging

U Panich, G Sittithumcharee… - Stem cells …, 2016 - Wiley Online Library
Skin is the largest human organ. Skin continually reconstructs itself to ensure its viability,
integrity, and ability to provide protection for the body. Some areas of skin are continuously …

Involvement of Nrf2 in myocardial ischemia and reperfusion injury

Y Shen, X Liu, J Shi, X Wu - International journal of biological …, 2019 - Elsevier
The morbidity rate of myocardial ischemia and reperfusion has increased in modern society,
and oxidative stress plays a critical role in the pathological process. Nuclear factor E2 …

Regulation of Nrf2/ARE pathway by dietary flavonoids: a friend or foe for cancer management?

T L. Suraweera, HPV Rupasinghe, G Dellaire, Z Xu - Antioxidants, 2020 - mdpi.com
The nuclear factor erythroid 2-related factor 2 (Nrf2)/antioxidant response element (ARE)
pathway is an important cell signaling mechanism in maintaining redox homeostasis in …

Natural polyphenols: a potential prevention and treatment strategy for metabolic syndrome

S Wang, Q Du, X Meng, Y Zhang - Food & Function, 2022 - pubs.rsc.org
Metabolic syndrome (MS) is the term for a combination of hypertension, dyslipidemia, insulin
resistance, and central obesity as factors leading to cardiovascular and metabolic disease …

[HTML][HTML] Ellagic acid ameliorates oxidative stress and insulin resistance in high glucose-treated HepG2 cells via miR-223/keap1-Nrf2 pathway

X Ding, T Jian, Y Wu, Y Zuo, J Li, H Lv, L Ma… - Biomedicine & …, 2019 - Elsevier
As a promising new target, miR-233 may regulate oxidative stress by targeting keap1-Nrf2
system to affect the pathological process of liver injury in T2DM. Ellagic acid (EA) is versatile …

Ellagic acid: Pharmacological activities and molecular mechanisms involved in liver protection

WR García-Niño, C Zazueta - Pharmacological Research, 2015 - Elsevier
Traditional drugs or therapies rarely have effects on regression of chronic liver diseases,
which result in many cases from sustained oxidative stress. In recent years, ellagic acid (EA) …

Oxidative stress, antioxidant capabilities, and bioavailability: Ellagic acid or urolithins?

S Alfei, B Marengo, G Zuccari - Antioxidants, 2020 - mdpi.com
Oxidative stress (OS), triggered by overproduction of reactive oxygen and nitrogen species,
is the main mechanism responsible for several human diseases. The available one-target …