A review of current trends with type 2 diabetes epidemiology, aetiology, pathogenesis, treatments and future perspectives

J Reed, S Bain, V Kanamarlapudi - Diabetes, Metabolic Syndrome …, 2021 - Taylor & Francis
Abstract Type 2 diabetes (T2D), which has currently become a global pandemic, is a
metabolic disease largely characterised by impaired insulin secretion and action. Significant …

Molecular mechanism of diabetic neuropathy and its pharmacotherapeutic targets

S Dewanjee, S Das, AK Das, N Bhattacharjee… - European journal of …, 2018 - Elsevier
Diabetic neuropathy is regarded as one of the most debilitating outcomes of diabetes
mellitus and may cause pain, decreased motility, and even amputation. Diabetic neuropathy …

Smoking, alcohol consumption, and 24 gastrointestinal diseases: Mendelian randomization analysis

S Yuan, J Chen, X Ruan, Y Sun, K Zhang, X Wang, X Li… - Elife, 2023 - elifesciences.org
Background: Whether the positive associations of smoking and alcohol consumption with
gastrointestinal diseases are causal is uncertain. We conducted this Mendelian …

Quantitative microbiome profiling disentangles inflammation-and bile duct obstruction-associated microbiota alterations across PSC/IBD diagnoses

S Vieira-Silva, J Sabino, M Valles-Colomer… - Nature …, 2019 - nature.com
Recent work has highlighted the importance of confounder control in microbiome
association studies,. For instance, multiple pathologies previously linked to gut ecosystem …

The enteric nervous system promotes intestinal health by constraining microbiota composition

AS Rolig, EK Mittge, J Ganz, JV Troll, E Melancon… - PLoS …, 2017 - journals.plos.org
Sustaining a balanced intestinal microbial community is critical for maintaining intestinal
health and preventing chronic inflammation. The gut is a highly dynamic environment …

The influence of diabetes on postoperative complications following colorectal surgery

DJH Tan, CYL Yaow, HT Mok, CH Ng, CH Tai… - Techniques in …, 2021 - Springer
Background Diabetes mellitus has been commonly associated with poor surgical outcomes.
The aim of this meta-analysis was to assess the impact of diabetes on postoperative …

Oxalate nephropathy: a review

JL Rosenstock, TMJ Joab, MV DeVita… - Clinical Kidney …, 2022 - academic.oup.com
This review describes the clinical and pathological features of oxalate nephropathy (ON),
defined as a syndrome of decreased renal function associated with deposition of calcium …

Review of gastroesophageal reflux disease (GERD) in the diabetic patient: 糖尿病患者的胃食管返流病(GERD) 综述

P Punjabi, A Hira, S Prasad, X Wang… - Journal of …, 2015 - Wiley Online Library
摘要本文对目前已知的糖尿病患者合并胃食管返流病(gastroesophageal reflux disease,
GERD) 的病理生理学机制进行了综述, 对目前人们关心的治疗方法进行了讨论, 为GERD …

The gut-kidney axis: putative interconnections between gastrointestinal and renal disorders

M Lehto, PH Groop - Frontiers in endocrinology, 2018 - frontiersin.org
Diabetic kidney disease (DKD) is a devastating condition associated with increased
morbidity and premature mortality. The etiology of DKD is still largely unknown. However …

Novel insights into the pathogenic impact of diabetes on the gastrointestinal tract

P Portincasa, L Bonfrate, DQH Wang… - European Journal of …, 2022 - Wiley Online Library
Type 2 and type 1 diabetes are common endocrine disorders with a progressively
increasing incidence worldwide. These chronic, systemic diseases have multiorgan …