Articular cartilage plays a vital role in the function of diarthrodial joints. Due to osteoarthritis
degeneration of articular cartilage occurs. The initial event that triggers the pathological …

Collagen is a crucial matrix component of articular cartilage. Because articular cartilage is a
load bearing tissue, developing mechanical integrity is a central goal of tissue engineering …

Drawing inspiration from examples by analogy can be a powerful tool for innovative design
during conceptual ideation but also carries the risk of negative design outcomes (eg, design …

Written by more than 400 subject experts representing diverse academic and applied
domains, this multidisciplinary resource surveys the vanguard of biomaterials and …

From a mechanical point of view, the most relevant components of articular cartilage are the
tight and highly organized collagen network together with the charged proteoglycans. Due to …

Replacement of degenerated cartilage with cell-based cartilage products may offer a long-
term solution to halt arthritis' degenerative progression. Chondrocytes are frequently used in …

Cartilage is a hydrated soft tissue whose solid matrix consists of negatively charged
proteoglycans enmeshed within a fibrillar collagen network. Though many aspects of …

Collagen fibrils networks in knee cartilage and menisci change in content and structure from
a region to another. While resisting tension, they influence global joint response as well as …

For this study, we hypothesized that the depth-dependent compressive equilibrium
properties of articular cartilage are the inherent consequence of its depth-dependent …

Load-bearing characteristics of articular cartilage are impaired during tissue degeneration.
Quantitative microscopy enables in vitro investigation of cartilage structure but determination …