The next frontier of environmental unknowns: substances of unknown or variable composition, complex reaction products, or biological materials (UVCBs)
Substances of unknown or variable composition, complex reaction products, or biological
materials (UVCBs) are over 70 000 “complex” chemical mixtures produced and used at …
materials (UVCBs) are over 70 000 “complex” chemical mixtures produced and used at …
Adding a new separation dimension to MS and LC–MS: what is the utility of ion mobility spectrometry?
Ion mobility spectrometry is an analytical technique known for more than 100 years, which
entails separating ions in the gas phase based on their size, shape, and charge. While ion …
entails separating ions in the gas phase based on their size, shape, and charge. While ion …
Rapid characterization of emerging per-and polyfluoroalkyl substances in aqueous film-forming foams using ion mobility spectrometry–mass spectrometry
Aqueous film-forming foams (AFFF) are mixtures formulated with numerous hydrocarbon-
and fluoro-containing surfactants. AFFF use leads to environmental releases of unknown per …
and fluoro-containing surfactants. AFFF use leads to environmental releases of unknown per …
Chemical and biological assessments of environmental mixtures: A review of current trends, advances, and future perspectives
Considering the chemical complexity and toxicity data gaps of environmental mixtures, most
studies evaluate the chemical risk individually. However, humans are usually exposed to a …
studies evaluate the chemical risk individually. However, humans are usually exposed to a …
[HTML][HTML] Grouping of UVCB substances with dose-response transcriptomics data from human cell-based assays
The application of in vitro biological assays as new approach methodologies (NAMs) to
support grouping of UVCB (unknown or variable composition, complex reaction products …
support grouping of UVCB (unknown or variable composition, complex reaction products …
Temporal chemical composition changes in water below a crude oil slick irradiated with natural sunlight
Photooxidation can alter the environmental fate and effects of spilled oil. To better
understand this process, oil slicks were generated on seawater mesocosms and exposed to …
understand this process, oil slicks were generated on seawater mesocosms and exposed to …
[HTML][HTML] Molecular formula assignment of dissolved organic matter by ultra-performance liquid chromatography quadrupole time-of-flight mass spectrometry using two …
P Aguilar-Alarcón, SV Gonzalez, Ø Mikkelsen… - Analytica Chimica …, 2024 - Elsevier
Background The accumulation of dissolved organic matter (DOM) poses an issue in the
management of the water quality from recirculating aquaculture systems (RAS), but its …
management of the water quality from recirculating aquaculture systems (RAS), but its …
[HTML][HTML] Grouping of UVCB substances with new approach methodologies (NAMs) data
One of the most challenging areas in regulatory science is assessment of the substances
known as UVCB (unknown or variable composition, complex reaction products and …
known as UVCB (unknown or variable composition, complex reaction products and …
[HTML][HTML] Integrative Chemical–Biological Grouping of Complex High Production Volume Substances from Lower Olefin Manufacturing Streams
Human cell-based test methods can be used to evaluate potential hazards of mixtures and
products of petroleum refining (“unknown or variable composition, complex reaction …
products of petroleum refining (“unknown or variable composition, complex reaction …
[HTML][HTML] Grouping of complex substances using analytical chemistry data: A framework for quantitative evaluation and visualization
A detailed characterization of the chemical composition of complex substances, such as
products of petroleum refining and environmental mixtures, is greatly needed in exposure …
products of petroleum refining and environmental mixtures, is greatly needed in exposure …