GTRD: an integrated view of transcription regulation

S Kolmykov, I Yevshin, M Kulyashov… - Nucleic acids …, 2021 - academic.oup.com
Abstract The Gene Transcription Regulation Database (GTRD; http://gtrd. biouml. org/)
contains uniformly annotated and processed NGS data related to gene transcription …

[HTML][HTML] Responsible, practical genomic data sharing that accelerates research

JB Byrd, AC Greene, DV Prasad, X Jiang… - Nature Reviews …, 2020 - nature.com
Data sharing anchors reproducible science, but expectations and best practices are often
nebulous. Communities of funders, researchers and publishers continue to grapple with …

The NHGRI-EBI GWAS Catalog: knowledgebase and deposition resource

E Sollis, A Mosaku, A Abid, A Buniello… - Nucleic acids …, 2023 - academic.oup.com
Abstract The NHGRI-EBI GWAS Catalog (www. ebi. ac. uk/gwas) is a FAIR knowledgebase
providing detailed, structured, standardised and interoperable genome-wide association …

The next-generation Open Targets Platform: reimagined, redesigned, rebuilt

D Ochoa, A Hercules, M Carmona… - Nucleic acids …, 2023 - academic.oup.com
Abstract The Open Targets Platform (https://platform. opentargets. org/) is an open source
resource to systematically assist drug target identification and prioritisation using publicly …

A compendium of uniformly processed human gene expression and splicing quantitative trait loci

N Kerimov, JD Hayhurst, K Peikova, JR Manning… - Nature …, 2021 - nature.com
Many gene expression quantitative trait locus (eQTL) studies have published their summary
statistics, which can be used to gain insight into complex human traits by downstream …

The MRC IEU OpenGWAS data infrastructure

B Elsworth, M Lyon, T Alexander, Y Liu, P Matthews… - BioRxiv, 2020 - biorxiv.org
Data generated by genome-wide association studies (GWAS) are growing fast with the
linkage of biobank samples to health records, and expanding capture of high-dimensional …

Open Targets Genetics: systematic identification of trait-associated genes using large-scale genetics and functional genomics

M Ghoussaini, E Mountjoy, M Carmona… - Nucleic acids …, 2021 - academic.oup.com
Abstract Open Targets Genetics (https://genetics. opentargets. org) is an open-access
integrative resource that aggregates human GWAS and functional genomics data including …

Open Targets Platform: supporting systematic drug–target identification and prioritisation

D Ochoa, A Hercules, M Carmona… - Nucleic acids …, 2021 - academic.oup.com
Abstract The Open Targets Platform (https://www. targetvalidation. org/) provides users with
a queryable knowledgebase and user interface to aid systematic target identification and …

The GTEx Consortium atlas of genetic regulatory effects across human tissues

GTEx Consortium - Science, 2020 - science.org
The Genotype-Tissue Expression (GTEx) project was established to characterize genetic
effects on the transcriptome across human tissues and to link these regulatory mechanisms …

The IntAct database: efficient access to fine-grained molecular interaction data

N Del Toro, A Shrivastava, E Ragueneau… - Nucleic acids …, 2022 - academic.oup.com
The IntAct molecular interaction database (https://www. ebi. ac. uk/intact) is a curated
resource of molecular interactions, derived from the scientific literature and from direct data …