GTRD: an integrated view of transcription regulation
S Kolmykov, I Yevshin, M Kulyashov… - Nucleic acids …, 2021 - academic.oup.com
Abstract The Gene Transcription Regulation Database (GTRD; http://gtrd. biouml. org/)
contains uniformly annotated and processed NGS data related to gene transcription …
contains uniformly annotated and processed NGS data related to gene transcription …
[HTML][HTML] Responsible, practical genomic data sharing that accelerates research
Data sharing anchors reproducible science, but expectations and best practices are often
nebulous. Communities of funders, researchers and publishers continue to grapple with …
nebulous. Communities of funders, researchers and publishers continue to grapple with …
The NHGRI-EBI GWAS Catalog: knowledgebase and deposition resource
E Sollis, A Mosaku, A Abid, A Buniello… - Nucleic acids …, 2023 - academic.oup.com
Abstract The NHGRI-EBI GWAS Catalog (www. ebi. ac. uk/gwas) is a FAIR knowledgebase
providing detailed, structured, standardised and interoperable genome-wide association …
providing detailed, structured, standardised and interoperable genome-wide association …
The next-generation Open Targets Platform: reimagined, redesigned, rebuilt
Abstract The Open Targets Platform (https://platform. opentargets. org/) is an open source
resource to systematically assist drug target identification and prioritisation using publicly …
resource to systematically assist drug target identification and prioritisation using publicly …
A compendium of uniformly processed human gene expression and splicing quantitative trait loci
N Kerimov, JD Hayhurst, K Peikova, JR Manning… - Nature …, 2021 - nature.com
Many gene expression quantitative trait locus (eQTL) studies have published their summary
statistics, which can be used to gain insight into complex human traits by downstream …
statistics, which can be used to gain insight into complex human traits by downstream …
The MRC IEU OpenGWAS data infrastructure
B Elsworth, M Lyon, T Alexander, Y Liu, P Matthews… - BioRxiv, 2020 - biorxiv.org
Data generated by genome-wide association studies (GWAS) are growing fast with the
linkage of biobank samples to health records, and expanding capture of high-dimensional …
linkage of biobank samples to health records, and expanding capture of high-dimensional …
Open Targets Genetics: systematic identification of trait-associated genes using large-scale genetics and functional genomics
Abstract Open Targets Genetics (https://genetics. opentargets. org) is an open-access
integrative resource that aggregates human GWAS and functional genomics data including …
integrative resource that aggregates human GWAS and functional genomics data including …
Open Targets Platform: supporting systematic drug–target identification and prioritisation
Abstract The Open Targets Platform (https://www. targetvalidation. org/) provides users with
a queryable knowledgebase and user interface to aid systematic target identification and …
a queryable knowledgebase and user interface to aid systematic target identification and …
The GTEx Consortium atlas of genetic regulatory effects across human tissues
GTEx Consortium - Science, 2020 - science.org
The Genotype-Tissue Expression (GTEx) project was established to characterize genetic
effects on the transcriptome across human tissues and to link these regulatory mechanisms …
effects on the transcriptome across human tissues and to link these regulatory mechanisms …
The IntAct database: efficient access to fine-grained molecular interaction data
N Del Toro, A Shrivastava, E Ragueneau… - Nucleic acids …, 2022 - academic.oup.com
The IntAct molecular interaction database (https://www. ebi. ac. uk/intact) is a curated
resource of molecular interactions, derived from the scientific literature and from direct data …
resource of molecular interactions, derived from the scientific literature and from direct data …