Eukaryotic nucleotide excision repair: from understanding mechanisms to influencing biology
Repair of bulky DNA adducts by the nucleotide excision repair (NER) pathway is one of the
more versatile DNA repair pathways for the removal of DNA lesions. There are two subsets …
more versatile DNA repair pathways for the removal of DNA lesions. There are two subsets …
DNA repair and damage pathways in breast cancer development and therapy
M Majidinia, B Yousefi - DNA repair, 2017 - Elsevier
DNA damage/repair constitutes several key pathways working in concert to eliminate DNA
lesions and maintain genome stability and integrity. Defective components in DNA damage …
lesions and maintain genome stability and integrity. Defective components in DNA damage …
[HTML][HTML] Biomarkers of psychological stress in health disparities research
Psychological stress can contribute to health disparities in populations that are confronted
with the recurring stress of everyday life. A number of biomarkers have been shown to be …
with the recurring stress of everyday life. A number of biomarkers have been shown to be …
Polygenic model of DNA repair genetic polymorphisms in human breast cancer risk
TR Smith, EA Levine, RI Freimanis, SA Akman… - …, 2008 - academic.oup.com
Genetic variations in DNA repair may impact repair functions, DNA damage and breast
cancer risk. Using data/samples collected from the first 752 Caucasians and 141 African …
cancer risk. Using data/samples collected from the first 752 Caucasians and 141 African …
Review of the gene‐environment interaction literature in cancer: what do we know?
NI Simonds, AA Ghazarian, CB Pimentel… - Genetic …, 2016 - Wiley Online Library
Background Risk of cancer is determined by a complex interplay of genetic and
environmental factors. Although the study of gene‐environment interactions (G× E) has been …
environmental factors. Although the study of gene‐environment interactions (G× E) has been …
The relationship between tobacco and breast cancer incidence: A systematic review and meta-analysis of observational studies
Y He, Y Si, X Li, J Hong, C Yu, N He - Frontiers in Oncology, 2022 - frontiersin.org
Background The effect of tobacco on breast cancer (BC) is controversial. The purpose of this
study was to investigate the relationship between tobacco and BC. Methods A search was …
study was to investigate the relationship between tobacco and BC. Methods A search was …
DNA repair gene polymorphisms and risk of adult meningioma, glioma, and acoustic neuroma
P Rajaraman, A Hutchinson, S Wichner… - Neuro …, 2010 - academic.oup.com
Although the etiology of primary brain tumors is largely unknown, prior studies suggest that
DNA repair polymorphisms may influence risk of glioma. Altered DNA repair is also likely to …
DNA repair polymorphisms may influence risk of glioma. Altered DNA repair is also likely to …
Associations of Lys939Gln and Ala499Val polymorphisms of the XPC gene with cancer susceptibility: A meta‐analysis
XPC polymorphisms may alter DNA repair capacity, thus leading to genetic instability and
carcinogenesis. Numerous studies have investigated the associations of XPC Lys939Gln …
carcinogenesis. Numerous studies have investigated the associations of XPC Lys939Gln …
Laryngeal cancer risk associated with smoking and alcohol consumption is modified by genetic polymorphisms in ERCC5, ERCC6 and RAD23B but not by …
R Abbasi, H Ramroth, H Becher, A Dietz… - … journal of cancer, 2009 - Wiley Online Library
Laryngeal cancer is known to be associated with smoking and high alcohol consumption.
Nucleotide excision repair (NER) plays a key role in repairing DNA damage induced by …
Nucleotide excision repair (NER) plays a key role in repairing DNA damage induced by …
A prospective study of smoking and breast cancer risk among African-American women
Purpose Active smoking and passive smoking have been associated with increased risk of
breast cancer. The purpose of the present study was to prospectively assess associations of …
breast cancer. The purpose of the present study was to prospectively assess associations of …