Immuno-thermal ablations–boosting the anticancer immune response

R Slovak, JM Ludwig, SN Gettinger, RS Herbst… - … for immunotherapy of …, 2017 - Springer
The use of immunomodulation to treat malignancies has seen a recent explosion in interest.
The therapeutic appeal of these treatments is far reaching, and many new applications …

Immunomodulation and targeted drug delivery with high intensity focused ultrasound (HIFU): Principles and mechanisms

H Ashar, A Ranjan - Pharmacology & Therapeutics, 2023 - Elsevier
High intensity focused ultrasound (HIFU) is a non-invasive and non-ionizing sonic energy-
based therapeutic technology for inducing thermal and non-thermal effects in tissues …

Microwave ablation enhances tumor-specific immune response in patients with hepatocellular carcinoma

K Leuchte, E Staib, M Thelen, P Gödel… - Cancer Immunology …, 2021 - Springer
Thermal ablative therapies are standard treatments for localized hepatocellular carcinoma
(HCC). In addition to local tumor destruction, ablation leads to abscopal effects in distant …

More than just tumor destruction: immunomodulation by thermal ablation of cancer

SP Haen, PL Pereira, HR Salih… - Journal of …, 2011 - Wiley Online Library
Over the past decades, thermoablative techniques for the therapy of localized tumors have
gained importance in the treatment of patients not eligible for surgical resection. Anecdotal …

Immunological effects of histotripsy for cancer therapy

A Hendricks-Wenger, R Hutchison… - Frontiers in …, 2021 - frontiersin.org
Cancer is the second leading cause of death worldwide despite major advancements in
diagnosis and therapy over the past century. One of the most debilitating aspects of cancer …

Reprogramming tumor microenvironment with photothermal therapy

Q Hu, Z Huang, Y Duan, Z Fu, B Liu - Bioconjugate Chemistry, 2020 - ACS Publications
The tumor microenvironment significantly influences cancer progression and therapeutic
response. Reprogramming of tumor microenvironment has emerged as a strategy to assist …

Progress in the cryoablation and cryoimmunotherapy for tumor

Z Chen, L Meng, J Zhang, X Zhang - Frontiers in immunology, 2023 - frontiersin.org
With the rapid advancement of imaging equipment and minimally invasive technology,
cryoablation technology is being used more frequently in minimally invasive treatment of …

A pan-cancer clinical study of personalized neoantigen vaccine monotherapy in treating patients with various types of advanced solid tumors

Y Fang, F Mo, J Shou, H Wang, K Luo, S Zhang… - Clinical Cancer …, 2020 - AACR
Purpose: Because of their high tumor specificity and immunogenicity, neoantigens have
been considered as ultimate targets for cancer immunotherapy. Neoantigen-based vaccines …

Elimination of metastatic melanoma using gold nanoshell-enabled photothermal therapy and adoptive T cell transfer

AS Bear, LC Kennedy, JK Young, SK Perna… - PloS one, 2013 - journals.plos.org
Ablative treatments such as photothermal therapy (PTT) are attractive anticancer strategies
because they debulk accessible tumor sites while simultaneously priming antitumor immune …

[HTML][HTML] Thermal ablation in non-small cell lung cancer: a review of treatment modalities and the evidence for combination with immune checkpoint inhibitors

K Rangamuwa, T Leong, C Weeden… - … lung cancer research, 2021 - ncbi.nlm.nih.gov
Lung cancer is the leading cause of cancer death worldwide, with approximately 1.6 million
cancer related deaths each year. Prognosis is best in patients with early stage disease …