An absolute, supraphysiologic elevation in GFR is observed early in the natural history in
10%–67% and 6%–73% of patients with type 1 and type 2 diabetes, respectively. Moreover …

Glomerular hyperfiltration is a phenomenon that can occur in various clinical conditions
including kidney disease. No single definition of glomerular hyperfiltration has been agreed …

OBJECTIVE To evaluate chronic kidney disease (CKD) and cardiovascular outcomes in
TECOS (Clinical trial reg. no. NCT00790205, clinicaltrials. gov) participants with type 2 …

Aims/hypothesis Glomerular hyperfiltration is a well-established phenomenon occurring
early in some patients with type 1 diabetes. However, there is no consistent answer …

[Formula: see text] Overweight and obesity are believed to be associated with renal damage.
Whether this depends on fat distribution is not known. We hypothesize that in addition to …

Previous studies have reported inconsistent results of the associations of alanine
transaminase (ALT), aspartate transaminase (AST), gamma-glutamyltransferase (GGT) and …

Background: Smoking induces albuminuria and accelerates progression to renal failure in
persons with diabetes, but little is known about the relation between smoking and renal …

Microalbuminuria (MA) is an important early sign of diabetic nephropathy. Hyperfiltration and
impaired filtration in relation to albuminuria has been well investigated in diabetic subjects …

Risk of radiocontrast nephropathy in patients with and without diabetes mellitus. The present
study was designed to test whether altered renovascular reactivity is associated with the …

Renal disease and hypertension in non–insulin-dependent diabetes mellitus. Recent
epidemiologic data demonstrate a dramatic increase in the incidence of end-stage renal …