Inflammation in chronic wounds

R Zhao, H Liang, E Clarke, C Jackson… - International journal of …, 2016 - mdpi.com
Non-healing chronic wounds present a major biological, psychological, social, and financial
burden on both individual patients and the broader health system. Pathologically extensive …

Extracellular matrix reorganization during wound healing and its impact on abnormal scarring

M Xue, CJ Jackson - Advances in wound care, 2015 - liebertpub.com
Significance: When a cutaneous injury occurs, the wound heals via a dynamic series of
physiological events, including coagulation, granulation tissue formation, re …

The cytoprotective protein C pathway

LO Mosnier, BV Zlokovic, JH Griffin - Blood, 2007 - ashpublications.org
Protein C is best known for its mild deficiency associated with venous thrombosis risk and
severe deficiency associated with neonatal purpura fulminans. Activated protein C (APC) …

Delivery systems of current biologicals for the treatment of chronic cutaneous wounds and severe burns

M Xue, R Zhao, H Lin, C Jackson - Advanced drug delivery reviews, 2018 - Elsevier
While wound therapy remains a clinical challenge in current medical practice, much effort
has focused on developing biological therapeutic approaches. This paper presents a …

Utilisation of chick embryo chorioallantoic membrane as a model platform for imaging-navigated biomedical research

L Chen, S Wang, Y Feng, J Zhang, Y Du, J Zhang… - Cells, 2021 - mdpi.com
The fertilised chick egg and particularly its chorioallantoic membrane (CAM) have drawn
continuing interest in biomedicine and bioengineering fields, especially for research on …

The science of wound bed preparation

J Panuncialman, V Falanga - Surgical Clinics of North America, 2009 - Elsevier
The concept of wound bed preparation (WBP) heralded a new era in terms of how we treat
wounds. It emphasized the difference between acute and chronic wounds, and it cemented …

A critical review on starch-based electrospun nanofibrous scaffolds for wound healing application

CP Palanisamy, B Cui, H Zhang… - International Journal of …, 2022 - Elsevier
Starch-based nanofibrous scaffolds exhibit a potential wound healing processes as they are
cost-effective, flexible, and biocompatible. Recently, natural polymers have received greater …

Targeting matrix metalloproteases to improve cutaneous wound healing

M Xue, NTV Le, CJ Jackson - Expert opinion on therapeutic targets, 2006 - Taylor & Francis
Wound repair is a physiological event in which tissue injury initiates a repair process leading
to restoration of structure and function of the tissue. Cutaneous wound repair can be divided …

Matrix metalloproteinases as therapeutic targets in protozoan parasitic infections

N Geurts, G Opdenakker, PE Van den Steen - Pharmacology & therapeutics, 2012 - Elsevier
Matrix metalloproteinases (MMPs) are associated with processes of tissue remodeling and
are expressed in all infections with protozoan parasites. We here report the status of MMP …

Advances in the modulation of cutaneous wound healing and scarring

MC Miller, J Nanchahal - BioDrugs, 2005 - Springer
Cutaneous wounds inevitably heal with scars, which can be disfiguring and compromise
function. In general, the greater the insult, the worse the scarring, although genetic make up …