Vitamin B12 deficiency
Abstract Vitamin B 12 (B12; also known as cobalamin) is a B vitamin that has an important
role in cellular metabolism, especially in DNA synthesis, methylation and mitochondrial …
role in cellular metabolism, especially in DNA synthesis, methylation and mitochondrial …
Mucosal ecological network of epithelium and immune cells for gut homeostasis and tissue healing
Y Kurashima, H Kiyono - Annual review of immunology, 2017 - annualreviews.org
The intestinal epithelial barrier includes columnar epithelial, Paneth, goblet,
enteroendocrine, and tuft cells as well as other cell populations, all of which contribute …
enteroendocrine, and tuft cells as well as other cell populations, all of which contribute …
Effect of host genetics on the gut microbiome in 7,738 participants of the Dutch Microbiome Project
Host genetics are known to influence the gut microbiome, yet their role remains poorly
understood. To robustly characterize these effects, we performed a genome-wide …
understood. To robustly characterize these effects, we performed a genome-wide …
Innate lymphoid cells regulate intestinal epithelial cell glycosylation
INTRODUCTION The combination of food intake and the resident gut microbiota exposes
the gastrointestinal (GI) tract to numerous antigens. Intestinal epithelial cells (ECs) compose …
the gastrointestinal (GI) tract to numerous antigens. Intestinal epithelial cells (ECs) compose …
Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci
We undertook a meta-analysis of six Crohn's disease genome-wide association studies
(GWAS) comprising 6,333 affected individuals (cases) and 15,056 controls and followed up …
(GWAS) comprising 6,333 affected individuals (cases) and 15,056 controls and followed up …
Power and instrument strength requirements for Mendelian randomization studies using multiple genetic variants
BL Pierce, H Ahsan… - International journal of …, 2011 - academic.oup.com
Abstract Background Mendelian Randomization (MR) studies assess the causality of an
exposure–disease association using genetic determinants [ie instrumental variables (IVs)] of …
exposure–disease association using genetic determinants [ie instrumental variables (IVs)] of …
Distribution and medical impact of loss-of-function variants in the Finnish founder population
Exome sequencing studies in complex diseases are challenged by the allelic heterogeneity,
large number and modest effect sizes of associated variants on disease risk and the …
large number and modest effect sizes of associated variants on disease risk and the …
Genome-wide association study identifies loci influencing concentrations of liver enzymes in plasma
Concentrations of liver enzymes in plasma are widely used as indicators of liver disease. We
carried out a genome-wide association study in 61,089 individuals, identifying 42 loci …
carried out a genome-wide association study in 61,089 individuals, identifying 42 loci …
[HTML][HTML] Sport nutrigenomics: personalized nutrition for athletic performance
NS Guest, J Horne, SM Vanderhout… - Frontiers in nutrition, 2019 - frontiersin.org
An individual's dietary and supplement strategies can influence markedly their physical
performance. Personalized nutrition in athletic populations aims to optimize health, body …
performance. Personalized nutrition in athletic populations aims to optimize health, body …
Fucosyltransferase 2 (FUT2) non-secretor status is associated with Crohn's disease
Genetic variation in both innate and adaptive immune systems is associated with Crohn's
disease (CD) susceptibility, but much of the heritability to CD remains unknown. We …
disease (CD) susceptibility, but much of the heritability to CD remains unknown. We …