A review of the traditional uses, pharmacology, and toxicology of areca nut

Z Wang, Z Guo, Y Luo, L Ma, X Hu, F Chen, D Li - Phytomedicine, 2024 - Elsevier
Background Areca nut, the fruit of A. catechu, is an important Chinese herbal medicine and
is the first of China's “four southern medicines”. The main chemical components are …

The Controversial Roles of Areca Nut: Medicine or Toxin?

PF Liu, YF Chang - International Journal of Molecular Sciences, 2023 - mdpi.com
Areca nut (AN) is used for traditional herbal medicine and social activities in several
countries. It was used as early as about AD 25-220 as a remedy. Traditionally, AN was …

Assessment of acute toxicity of crude extract rich in carotenoids from Cantaloupe melon (Cucumis melo L.) and the gelatin-based nanoparticles using the zebrafish …

T dos Santos Pais, AC Luchiari, AM de Souza… - Food and Chemical …, 2023 - Elsevier
Cantaloupe melon is known for its carotenoid-rich orange pulp. However, carotenoids are
sensitive to oxygen, light, and heat, potentially reducing their benefits. Nanoencapsulation …

Oxidative stress and endoplasmic reticulum stress contributes to arecoline and its secondary metabolites-induced dyskinesia in zebrafish embryos

W Yan, T Zhang, S Li, Y Wang, L Zhu, Y Cao… - International Journal of …, 2023 - mdpi.com
Areca nut has been listed as one of the most addictive substances, along with tobacco,
alcohol and caffeine. Areca nut contains seven psychoactive alkaloids; however, the effects …

[HTML][HTML] Recent Advance on Biological Activity and Toxicity of Arecoline in Edible Areca (Betel) Nut: A Review

G Huang, D Zeng, T Liang, Y Liu, F Cui, H Zhao, W Lu - Foods, 2024 - mdpi.com
Areca nut (Areca catechu L. AN), which is the dried, mature seed of the palm species Areca
catechu L., is consumed by over 600 million individuals, predominantly in South Asia, East …

Comprehensive insights into areca nut: active components and omics technologies for bioactivity evaluation and quality control

Y Sun, J Feng, W Hou, H Qi, Y Liu - Frontiers in Pharmacology, 2024 - frontiersin.org
Areca nut (AN), the fruit or seed of Areca catechu Linn, has many uses, including chewing
and medicinal purposes. It has sparked worries about health due to the presence of …

Evaluation of sub-chronic toxicity of melamine via systematic or oral delivery in adult zebrafish based on behavioral endpoints

HC Chen, WW Feng, G Audira, KA Kurnia, SH Hung… - NeuroToxicology, 2024 - Elsevier
Melamine-tainted products have been found in the market and raised issues about food
safety. Recent studies done in rodents and humans demonstrated the toxicities of melamine …

[HTML][HTML] In vitro hydrolysis of areca nut xenobiotics in human liver

V Paolillo, M Jayakumar, C Sheperd, A Tran… - Drug Metabolism and …, 2025 - Elsevier
Areca nut (AN) is a substance of abuse consumed by millions worldwide, in spite of
established oral and systemic toxicities associated with its use. Previous research …

A Mechanistic Study of the Osteogenic Effect of Arecoline in an Osteoporosis Model: Inhibition of Iron Overload-Induced Osteogenesis by Promoting Heme Oxygenase …

Z Jiang, L Deng, G Xiang, X Xu, Y Wang - Antioxidants, 2024 - mdpi.com
Iron overload-associated osteoporosis presents a significant challenge to bone health. This
study examines the effects of arecoline (ACL), an alkaloid found in areca nut, on bone …

Biodiversity conservation, food security, and carbon storage potential of local agroforestry practices in the Bird's Head Region of Papua, Indonesia

H HENDRI, JDWI NUGROHO… - Biodiversitas Journal of …, 2024 - smujo.id
Hendri, Nugroho JD, Rahmadaniarti A, Nurlaela, Prabawardani S, Luhulima FDN, Gardiner
C, Hematang F. 2024. Biodiversity conservation, food security, and carbon storage potential …