Fundamentals and methods for T‐and B‐cell epitope prediction
JL Sanchez-Trincado… - Journal of …, 2017 - Wiley Online Library
Adaptive immunity is mediated by T‐and B‐cells, which are immune cells capable of
developing pathogen‐specific memory that confers immunological protection. Memory and …
developing pathogen‐specific memory that confers immunological protection. Memory and …
Epitope-based vaccine design: a comprehensive overview of bioinformatics approaches
Highlights•Epitope vaccines provide maximal therapeutic efficacy with minimal side
effects.•Reverse vaccinology can be used for designing epitope vaccines.•Computational …
effects.•Reverse vaccinology can be used for designing epitope vaccines.•Computational …
Machine learning techniques for the prediction of B-cell and T-cell epitopes as potential vaccine targets with a specific focus on SARS-CoV-2 pathogen: A review
SNH Bukhari, A Jain, E Haq, A Mehbodniya, J Webber - Pathogens, 2022 - mdpi.com
The only part of an antigen (a protein molecule found on the surface of a pathogen) that is
composed of epitopes specific to T and B cells is recognized by the human immune system …
composed of epitopes specific to T and B cells is recognized by the human immune system …
Allergic diseases: a comprehensive review on risk factors, immunological mechanisms, link with COVID-19, potential treatments, and role of allergen bioinformatics
FM Aldakheel - International Journal of Environmental Research and …, 2021 - mdpi.com
The prevalence of allergic diseases is regarded as one of the key challenges in health
worldwide. Although the precise mechanisms underlying this rapid increase in prevalence …
worldwide. Although the precise mechanisms underlying this rapid increase in prevalence …
In silico T cell epitope identification for SARS-CoV-2: Progress and perspectives
Growing evidence suggests that T cells may play a critical role in combating severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2). Hence, COVID-19 vaccines that can …
respiratory syndrome coronavirus 2 (SARS-CoV-2). Hence, COVID-19 vaccines that can …
Immunoinformatics-guided design of an epitope-based vaccine against severe acute respiratory syndrome coronavirus 2 spike glycoprotein
A Rakib, SA Sami, NJ Mimi, MM Chowdhury… - Computers in biology …, 2020 - Elsevier
Aims With a large number of fatalities, coronavirus disease-2019 (COVID-19) has greatly
affected human health worldwide. Severe acute respiratory syndrome coronavirus 2 (SARS …
affected human health worldwide. Severe acute respiratory syndrome coronavirus 2 (SARS …
Novel in silico tools for designing peptide-based subunit vaccines and immunotherapeutics
The conventional approach for designing vaccine against a particular disease involves
stimulation of the immune system using the whole pathogen responsible for the disease. In …
stimulation of the immune system using the whole pathogen responsible for the disease. In …
Multiepitope Subunit Vaccine Design against COVID‐19 Based on the Spike Protein of SARS‐CoV‐2: An In Silico Analysis
The global health crisis caused by severe acute respiratory syndrome coronavirus 2 (SARS‐
CoV‐2), the causal agent of COVID‐19, has resulted in a negative impact on human health …
CoV‐2), the causal agent of COVID‐19, has resulted in a negative impact on human health …
[HTML][HTML] In silico design of a promiscuous chimeric multi-epitope vaccine against Mycobacterium tuberculosis
BT Andongma, Y Huang, F Chen, Q Tang… - Computational and …, 2023 - Elsevier
Tuberculosis (TB) is a global health threat, killing approximately 1.5 million people each
year. The eradication of Mycobacterium tuberculosis, the main causative agent of TB, is …
year. The eradication of Mycobacterium tuberculosis, the main causative agent of TB, is …
From ZikV genome to vaccine: in silico approach for the epitope‐based peptide vaccine against Zika virus envelope glycoprotein
Zika virus (ZikV) has emerged as a potential threat to human health worldwide. A member of
the Flaviviridae, ZikV is transmitted to humans by mosquitoes. It is related to other …
the Flaviviridae, ZikV is transmitted to humans by mosquitoes. It is related to other …