Drug-induced liver injury (DILI) is an adverse reaction to drugs or other xenobiotics that
occurs either as a predictable event when an individual is exposed to toxic doses of some …

Liver disease accounts for approximately 2 million deaths per year worldwide, 1 million due
to complications of cirrhosis and 1 million due to viral hepatitis and hepatocellular …

Abbreviations: AASLD, American Association for the Study of Liver Diseases; AIH,
autoimmune hepatitis; ALF, acute liver failure; ALT, alanine aminotransferase; AMA …

Drug-Induced Liver Injury The liver has a range of responses to drug-induced injury, with a
number of phenotypes. In addition, idiosyncratic reactions may occur as a consequence of …

Drug induced liver injury (DILI) is a relatively rare hepatic condition in response to the use of
medications, illegal drugs, herbal products or dietary supplements. It occurs in susceptible …

There are currently more than 1000 prescription medications available for use in the United
States and more than 100,000 over-the-counter herbal and dietary supplements (HDS) …

Background & Aims We performed a nationwide, retrospective study to determine the
incidence and causes of drug-induced liver injury (DILI) in mainland China. Methods We …

Idiosyncratic (unpredictable) drug-induced liver injury is one of the most challenging liver
disorders faced by hepatologists, because of the myriad of drugs used in clinical practice …

Fibrosis is the abnormal deposition of extracellular matrix, which can lead to organ
dysfunction, morbidity, and death. The disease burden caused by fibrosis is substantial, and …

The first consensus report of the working party of the Asian Pacific Association for the Study
of the Liver (APASL) set up in 2004 on acute-on-chronic liver failure (ACLF) was published …