Tumorigenesis is a complex and dynamic process, consisting of three stages: initiation,
progression, and metastasis. Tumors are encircled by extracellular matrix (ECM) and …

Obesity-related breast cancer is an important threat that affects especially post-menopausal
women. The link between obesity and breast cancer seems to be relying on the …

Botanical dietary supplements are increasingly popular for women's health, particularly for
older women. The specific botanicals women take vary as a function of age. Younger …

Obesity and its associated metabolic dysregulation are established risk factors for many
cancers. However, the biologic mechanisms underlying this relationship remain …

Abstract Aromatase (estrogen synthetase; EC 1.14. 14.1) catalyzes the demethylation of
androgens' carbon 19, producing phenolic 18-carbon estrogens. Aromatase is most widely …

Olive oil (OO) is the main source of added fat in the Mediterranean diet (MD). It is a mix of
bioactive compounds, including monounsaturated fatty acids, phytosterols, simple phenols …

Whilst previous studies have reported that higher BMI increases a woman's risk of
developing ovarian cancer, associations for the different histological subtypes have not …

Metabolic syndrome is a type of multifactorial metabolic disease with the presence of at least
three factors: obesity, diabetes mellitus, low high-density lipoprotein, hypertriglyceridemia …

Many inflammation-associated diseases, including cancers, increase in women after
menopause and with obesity. In contrast to anti-inflammatory actions of 17β-estradiol, we …

Obesity, defined as a body mass index (BMI)≥ 30, is an established risk factor for breast
cancer among women in the general population after menopause. Whether elevated BMI is …