Current state of evidence: influence of nutritional and nutrigenetic factors on immunity in the COVID-19 pandemic framework

S Galmés, F Serra, A Palou - Nutrients, 2020 - mdpi.com
The pandemic caused by the new coronavirus has caused shock waves in many countries,
producing a global health crisis worldwide. Lack of knowledge of the biological mechanisms …

Peripheral blood cells, a transcriptomic tool in nutrigenomic and obesity studies: current state of the art

B Reynés, T Priego, M Cifre, P Oliver… - … reviews in food science …, 2018 - Wiley Online Library
Gene expression profile of peripheral blood cells (PBC) is able to reflect useful aspects of
the whole body metabolic status. Therefore, and favored by the huge development of “omic” …

Lycium barbarum polysaccharide modulates gut microbiota to alleviate rheumatoid arthritis in a rat model

W Lai, C Wang, R Lai, X Peng, J Luo - npj Science of Food, 2022 - nature.com
Rheumatoid arthritis (RA) seriously impairs the quality of life of sufferers. It has been shown
that Lycium barbarum polysaccharide (LBP), a natural active indigestible ingredient with …

Use of human PBMC to analyse the impact of obesity on lipid metabolism and metabolic status: a proof-of-concept pilot study

A Costa, B Reynés, J Konieczna, M Martín, M Fiol… - Scientific reports, 2021 - nature.com
Peripheral blood mononuclear cells (PBMC) are widely used as a biomarker source in
nutrition/obesity studies because they reflect gene expression profiles of internal tissues. In …

A genetic score of predisposition to low-grade inflammation associated with obesity may contribute to discern population at risk for metabolic syndrome

S Galmés, M Cifre, A Palou, P Oliver, F Serra - Nutrients, 2019 - mdpi.com
Omega-3 rich diets have been shown to improve inflammatory status. However, in an ex vivo
system of human blood cells, the efficacy of eicosapentaenoic acid (EPA) and …

Effects of fish and krill oil on gene expression in peripheral blood mononuclear cells and circulating markers of inflammation: a randomised controlled trial

A Rundblad, KB Holven, I Bruheim… - Journal of nutritional …, 2018 - cambridge.org
Marine n-3 (omega-3) fatty acids alter gene expression by regulating the activity of
transcription factors. Krill oil is a source of marine n-3 fatty acids that has been shown to …

Effect of free fatty acids on inflammatory gene expression and hydrogen peroxide production by ex vivo blood mononuclear cells

A Sureda, M Martorell, MM Bibiloni, C Bouzas… - Nutrients, 2020 - mdpi.com
The aim of this study was to assess free fatty acids'(FAs) ex vivo anti-/proinflammatory
capabilities and their influence on inflammatory gene expression and H2O2 production by …

Aptamer-functionalized AuNCs nanogel for targeted delivery of docosahexaenoic acid to induce browning of white adipocytes

H Xu, J Ding, Y Du, L Li, Y Li, M Zhao, Y Su… - Journal of Materials …, 2023 - pubs.rsc.org
Obesity, as a global public health concern, causes a series of metabolic disorders and other
diseases. Browning of white fat (white adipocytes transforming to beige adipocytes) offers an …

Peripheral blood mononuclear cells antioxidant adaptations to regular physical activity in elderly people

C Busquets-Cortés, X Capó, MM Bibiloni, M Martorell… - Nutrients, 2018 - mdpi.com
Regular physical activity prescription is a key point for healthy aging and chronic disease
management and prevention. Our aim was to evaluate the antioxidant defense system and …

Dietary Sources, Sex, and rs5888 (SCARB1) as Modulators of Vitamin A's Effect on Cardiometabolic Health

S Galmés, A Palou, F Serra - International journal of molecular sciences, 2023 - mdpi.com
Although preclinical studies have attributed vitamin A (VA) cardiometabolic benefits, these
effects are still controversial and not always supported in large human studies. Here, the …